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Inhibitors & Agonists
Angiogenesis
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Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
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Boronic Acids
Bromides
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Iodos
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Name Index S
SMER28
(Catalog# : 17011709, Cas# :
307538-42-7
)
SMER28 is a small molecule modulator of autophagy, inducing autophagy independently o
SKF-38393 hydrochloride
(Catalog# : 17011707, Cas# :
62717-42-4
)
SKF-38393, aslo known as (+/-)-SKF-38393, is a synthetic compound of the benzazepine
Sitafloxacin anhydrous
(Catalog# : 17011706, Cas# :
127254-12-0
)
Sitafloxacin is a new-generation, broad-spectrum oral fluoroquinolone that is very ac
SHP099 HCl
(Catalog# : 17011704, Cas# :
1801747-11-4
)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
Shogaol (6-Shogaol)
(Catalog# : 17011703, Cas# :
555-66-8
)
Shogaol, also known as (6)-shogaol, is a pungent constituent of ginger similar in che
SGC707
(Catalog# : 17011702, Cas# :
1687736-54-4
)
SGC707 is a potent, selective and cell-active allosteric inhibitor of protein arginin
SC66
(Catalog# : 17011701, Cas# :
871361-88-5
)
SC66 is a novel and potent AKT inhibitor, which reduced cell viability in a dose- and
SBI0206965
(Catalog# : 71161, Cas# :
1884220-36-3
)
SBI0206965 is a potent and selective autophagy Kinase ULK1 Inhibitor. Many tumors bec
SB-743921 HCl
(Catalog# : 17011609, Cas# :
940929-33-9
)
SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-
Sardomozide
(Catalog# : 17011607, Cas# :
149400-88-4
)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
SAR407899 HCl
(Catalog# : 17011606, Cas# :
923262-96-8
)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
SAR131675
(Catalog# : 17011605, Cas# :
1092539-44-0
)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
4SC-202
(Catalog# : 161227110, Cas# :
910462-43-0
)
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone de
SKL2001
(Catalog# : 16122784, Cas# :
909089-13-0
)
SKL2001 is a novel agonist of the Wnt/-catenin pathway that disrupts the Axin/-cateni
Salicylanilide
(Catalog# : 16122766, Cas# :
87-17-2
)
Salicylanilides are a group of compounds with a wide range of biological activities i
Sivelestat (ONO-5046)
(Catalog# : 16122760, Cas# :
127373-66-4
)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
Sivelestat sodium
(Catalog# : 16122758, Cas# :
201677-61-4
)
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhib
SC75741
(Catalog# : 16122748, Cas# :
913822-46-5
)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
SQ22536
(Catalog# : 16122726, Cas# :
17318-31-9
)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
SIS3
(Catalog# : 16122721, Cas# :
521984-48-5
)
SIS3, a novel specific inhibitor of Smad3, inhibits TGF- and activin signaling by sup
Saccharin 1-methylimidazole (SMI)
(Catalog# : 16122716, Cas# :
482333-74-4
)
SMI is considered a general-purpose activator for DNA and RNA synthesis.
STA-21
(Catalog# : 16122706, Cas# :
111540-00-2
)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
SKI II
(Catalog# : 6111526, Cas# :
312636-16-1
)
SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 M
SR1001
(Catalog# : 6111522, Cas# :
1335106-03-0
)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
S1P1 Agonist III
(Catalog# : 61119, Cas# :
1324003-64-6
)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
SCH 546738
(Catalog# : 161113, Cas# :
906805-42-3
)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
4SC-202
(Catalog# : 611937, Cas# :
1186222-89-8
)
4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes(NO H
SJB3-019A
(Catalog# : 611930, Cas# :
2070015-29-9
)
SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 ti
SR-3029
(Catalog# : 611915, Cas# :
1454585-06-8
)
SR 3029 is a potent and highly specific CK1/CK1 inhibitor with the IC50 of 97 nM.SR-3
SB-216763
(Catalog# : 161009026, Cas# :
280744-09-4
)
SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
AZD0095
(Catalog# : 237072, Cas# :
2750001-23-9
)
AZD0095 is a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology.
2-MNG
(Catalog# : 24129, Cas# :
2101538-28-5
)
2-MNG is a new potent melanogenesis inhibitor, which exhibits a unique mode of action
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-