SC66
Catalog No: 17011701
CAS Number: 871361-88-5
Purity: 98%
SC66 is a novel and potent AKT inhibitor, which reduced cell viability in a dose- and time-dependent manner, inhibited colony formation and induced apoptosis in HCC cells. SC66 treatment led to a reduction in total and phospho-AKT levels. SC66 significantly potentiated the effects of both conventional chemotherapeutic and targeted agents, doxorubicin and everolimus, respectively. In vivo, SC66 inhibited tumor growth of Hep3B cells in xenograft models, with a similar mechanism observed in the in vitro model. SC66 had antitumor effects on HCC cells.
For research use only. We do not sell to patients.
Chemical Information
| Name | SC66 |
|---|---|
| Iupac Chemical Name | (2E,6E)-2,6-bis(pyridin-4-ylmethylene)cyclohexanone |
| Synonyms | SC66; SC 66 |
| Molecular Formula | C18H16N2O |
| Molecular Weight | 276.33 |
| Smile | N1=CC=C(C=C1)\C=C/1\C(/C(/CCC1)=C/C1=CC=NC=C1)=O |
| InChiKey | CYVVJSKZRBZHAV-UNZYHPAISA-N |
| InChi | InChI=1S/C18H16N2O/c21-18-16(12-14-4-8-19-9-5-14)2-1-3-17(18)13-15-6-10-20-11-7-15/h4-13H,1-3H2/b16-12+,17-13+ |
| CAS Number | 871361-88-5 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
