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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
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Bromides
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Deuterated
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Indoles and Oxindoles
Iodos
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Name Index S
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat is an antineoplastic drug candidate.
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat is a rotamase inhibitor and vascular endothelial growth factor (VEGF) pro
Saridegib
(Catalog# : 1812251, Cas# :
1037210-93-7
)
Saridegib, also known as IPI-926, is an orally bioavailable, cyclopamine-derived inhi
SAR260301
(Catalog# : 1812134, Cas# :
1260612-13-2
)
SAR260301 is potent and selective Class I phosphatidylinositol-3-kinase (PI3K)β spec
Sparsentan
(Catalog# : 1812132, Cas# :
254740-64-2
)
Sparsentan, also known as RE-021, PS433540 and DARA-a, is a Dual angiotensin II and e
SR-0987
(Catalog# : 1810263, Cas# :
303126-97-8
)
SR-0987 is a T cell-specific RORγ (RORγt) agonist. SR-0987 induces IL-17 expression
SGC-CBP30
(Catalog# : 1810244, Cas# :
1613695-14-9
)
SGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are ge
ST2825
(Catalog# : 1810243, Cas# :
894787-30-5
)
ST-2825 is MyD88 inhibitor. ST2825 provides neuroprotection after experimental trauma
Seletalisib
(Catalog# : 1810221, Cas# :
1362850-20-1
)
Seletalisib, also known as UCB-5857, is a potent and selective PI3 kinase inhibitor,
Simenepag
(Catalog# : 1810172, Cas# :
910562-15-1
)
Simenepag, also known as AGN-210676, is a small molecule prostaglandin E2 receptor ag
SB-273005
(Catalog# : 186221, Cas# :
205678-31-5
)
SB-273005 is an inhibitor of integrin αvβ3.
STF-083010
(Catalog# : 185151, Cas# :
307543-71-1
)
STF-083010, also known as IRE1 Inhibitor I, is an inhibitor of the IRE1/XBP1 pathway.
SAR407899 free base
(Catalog# : 185115, Cas# :
923359-38-0
)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
SB-334867 free base
(Catalog# : 185114, Cas# :
792173-99-0
)
SB-334867 is an orexin antagonist.
SC-560
(Catalog# : 185113, Cas# :
188817-13-2
)
SC-560 is a potent, orally active and selective inhibitor of COX-1.
Seladelpar
(Catalog# : 185112, Cas# :
851528-79-5
)
Seladelpar, also known as MBX-8025 and RWJ-800025, is a selective peroxisome prolifer
SEL120-34A HCl
(Catalog# : 18574, Cas# :
1609452-30-3
)
SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high lev
SR-4370
(Catalog# : 1842814, Cas# :
1816294-67-3
)
SR-4370 is an HDAC inhibitor.
SGC2085 HCl
(Catalog# : 184287, Cas# :
1821908-49-9
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
S38093 HCl
(Catalog# : 184176, Cas# :
1222097-72-4
)
S38093 is an inverse agonist at histamine H3 receptors.
STO-609 acetate
(Catalog# : 184123, Cas# :
1173022-21-3
)
STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases
Super-TDU
(Catalog# : 18495, Cas# :
1599441-71-0
)
Super-TDU is an inhibitory polypeptide targeting yap-teads interaction.
SSD114 HCl
(Catalog# : 18427, Cas# :
N/A
)
SSD114 is a GABAB positive allosteric modulator. SSD114 potentiated GABA-stimulated [
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)methyl 2,4-dimethylbenzoate
(Catalog# : 183219, Cas# :
1253955-19-9
)
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)met
(S)-Butyl 2-hydroxybutanoate
(Catalog# : 1712291, Cas# :
132513-51-0
)
butyl (2S)-2-hydroxybutanoate is building blocks.
SCR7 pyrazine
(Catalog# : 1712261, Cas# :
14892-97-8
)
SCR7 pyrazine is a small molecule inhibitor of DNA ligase IV that prevents nonhomolog
S38093
(Catalog# : 17101615, Cas# :
862896-30-8
)
S 38093 is a brain-penetrant antagonist of H3 receptor, with Ki of 8.8, 1.44 and 1.2
SAR-7334 HCl
(Catalog# : 17101610, Cas# :
1333207-63-8
)
SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that o
SEN-826
(Catalog# : 1710168, Cas# :
1160833-51-1
)
SEN-826 is a potential anticancer agent.
SRT3025 HCl
(Catalog# : 17101310, Cas# :
2070015-26-6
)
SRT3025 is an orally available small molecule activator of the SIRT1 enzyme.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
NSC624206
(Catalog# : 26A028, Cas# :
13116-77-3
)
NSC624206 is a Ub E1 inhibitor that specifically inhibits thioester bond formation be
CVN-424 ( Solangepras )
(Catalog# : 26A025, Cas# :
2254706-21-1
)
CVN-424 (Solengepras) is a first-in-class, small molecule GPR6 inverse agonist.
(R)-4-(3-fluoro-5-(trimethylstannyl)phenyl)-1-((3-methylpyridin-4-yl)methyl)pyrrolidin-2-one
(Catalog# : 26A027, Cas# :
2289636-79-7
)
Mutant IDH1/NAMPT-IN-1
(Catalog# : 26A032, Cas# :
3040122-14-0
)
Mutant IDH1/NAMPT-IN-1 ( compound 23h ) has excellent and balanced inhibitory activit
Zervimesine ( CT1812 )
(Catalog# : 193283, Cas# :
1802632-22-9
)
CT-1812 is a first-in-class, orally available sigma-2/PGRMC1 antagonist (alpha beta o
BLU-808
(Catalog# : 26A024, Cas# :
3041025-10-6
)
BLU-808 is a Potent and Selective Small Molecule Inhibitor of Wild-type c-KIT for Mas
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t