MRT-2359 is a potent, highly selective, and orally bioavailable investigational molecular glue degrader (MGD) of GSPT1.
For research use only. We do not sell to patients.
| Name | MRT-2359 |
|---|---|
| Iupac Chemical Name | (2-(2,6-dioxopiperidin-3-yl)-3-oxoisoindolin-5-yl)methyl (2-fluoro-5-(trifluoromethoxy)phenyl)carbamate |
| Synonyms | MRT-2359; MRT 2359; MRT2359 |
| Molecular Formula | C22H17F4N3O6 |
| Molecular Weight | 495.39 |
| Smile | O=C1NC(C(N2CC(C=CC(COC(NC3=CC(OC(F)(F)F)=CC=C3F)=O)=C4)=C4C2=O)CC1)=O |
| InChiKey | HNTGMIGBGVFOBT-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H17F4N3O6/c23-15-4-3-13(35-22(24,25)26)8-16(15)27-21(33)34-10-11-1-2-12-9-29(20(32)14(12)7-11)17-5-6-18(30)28-19(17)31/h1-4,7-8,17H,5-6,9-10H2,(H,27,33)(H,28,30,31) |
| CAS Number | 2803881-11-8 |
| Related CAS | 2803881-11-8 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |