MRT-6160
Catalog No: 26A100
CAS Number: 3050683-38-7
Purity: ≧98.0%
MRT-6160 is a highly selective first-in-class oral VAV1-targeting molecular glue degrader (MGD), which induces proteasomal degradation of VAV1 through formation of a ternary complex with the E3 ligase cereblon.
For research use only. We do not sell to patients.
Chemical Information
| Name | MRT-6160 |
|---|---|
| Iupac Chemical Name | 3-(2-chloro-4'-(2-oxopyridin-1(2H)-yl)-[1,1'-biphenyl]-3-yl)piperidine-2,6-dione |
| Synonyms | MRT-6160; MRT 6160; MRT6160 |
| Molecular Formula | C22H17ClN2O3 |
| Molecular Weight | 392.84 |
| Smile | O=C1N(C2=CC=C(C3=CC=CC(C4CCC(NC4=O)=O)=C3Cl)C=C2)C=CC=C1 |
| InChiKey | RIFDPWJLHNZGEX-UHFFFAOYSA-N |
| InChi | InChI=1S/C22H17ClN2O3/c23-21-16(4-3-5-17(21)18-11-12-19(26)24-22(18)28)14-7-9-15(10-8-14)25-13-2-1-6-20(25)27/h1-10,13,18H,11-12H2,(H,24,26,28) |
| CAS Number | 3050683-38-7 |
| Related CAS | 3050683-38-7 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
