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SC75741

Catalog No.: 16122748
Cas No.: 913822-46-5
Purity : 98% 
16122748 - SC75741 | CAS 913822-46-5

Catalog number : 16122748

CAS number : 913822-46-5

Molecular Formula : C29H23N7O2S2 

Molecular Weight : 565.67 

Iupac Chemical Name : SC75741 

Smile : c1ccc(cc1)C(=O)c2ccc3c(c2)[nH]c(n3)NC(=O)c4csc(n4)C5CCN(CC5)c6c7c(ccs7)ncn6

InChiKey : QNZVBFMXWNWVKG-UHFFFAOYSA-N

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SynonymsN/A 
Molecular FormulaC29H23N7O2S2 
Molecular Weight565.67 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Smilec1ccc(cc1)C(=O)c2ccc3c(c2)[nH]c(n3)NC(=O)c4csc(n4)C5CCN(CC5)c6c7c(ccs7)ncn6
InChiKeyQNZVBFMXWNWVKG-UHFFFAOYSA-N
InChiInChI=1S/C29H23N7O2S2/c37-24(17-4-2-1-3-5-17)19-6-7-20-22(14-19)34-29(33-20)35-27(38)23-15-40-28(32-23)18-8-11-36(12-9-18)26-25-21(10-13-39-25)30-16-31-26/h1-7,10,13-16,18H,8-9,11-12H2,(H2,33,34,35,38)
MDLMFCD18206785
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SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressive activity by inhibiting human PBMC proliferation with IC50 of 2.2 M. SC75741 inhibits replication of influenza A and B viruses by inhibiting NF-B-mediated signalling on a transcriptional level. Moreover, SC75741 shows a high barrier for development of resistant virus variants. 

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