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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index S
SGI-110
(Catalog# : 011806, Cas# :
929901-49-5
)
SGI-110 is a small molecule, DNMT inhibitor with demonstrated activity in restoring s
SC144
(Catalog# : 011313, Cas# :
895158-95-9
)
SC144 is the first-in-class orally active small-molecule gp130 inhibitor.
SKF-86002
(Catalog# : 011308, Cas# :
72873-74-6
)
SKF-86002 is a potent inhibitor of p38 MAP kinase wit IC50 of 0.5-1 uM.
SD-208
(Catalog# : 011304, Cas# :
627536-09-8
)
SD-208 is a potent, orally active ATP-competitive transforming growth factor- recepto
SCH772984
(Catalog# : 11106, Cas# :
942183-80-4
)
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respec
Savolitinib(Volitinib)
(Catalog# : 010805, Cas# :
1313725-88-0
)
Savolitinib is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase
SF1126
(Catalog# : 010804, Cas# :
936487-67-1
)
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibi
Staurosporine
(Catalog# : 010601, Cas# :
62996-74-1
)
Staurosporine is a prototypical potent ATP-competitive kinase inhibitor with IC50 of
SCH900776 S-isomer
(Catalog# : 010438, Cas# :
891494-64-7
)
SCH900776 (S-isomer) is the S-isomer form of SCH900776(HY-15532), which is a potent,
SB 242084
(Catalog# : 010427, Cas# :
181632-25-7
)
SB 242084 is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold se
SB 415286
(Catalog# : 010425, Cas# :
264218-23-7
)
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3
SGI-1776
(Catalog# : 122945, Cas# :
1025065-69-3
)
SGI-1776 is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM; 50- and 10-f
Sonolisib
(Catalog# : 122944, Cas# :
502632-66-8
)
Sonolisib is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and
Soraphen A
(Catalog# : 122922, Cas# :
122547-72-2
)
Coming soon!
Sembragiline
(Catalog# : 122921, Cas# :
676479-06-4
)
Coming soon!
Saracatinib
(Catalog# : 122913, Cas# :
379231-04-6
)
Saracatinib is an orally available 5-, 7-substituted anilinoquinazoline with anti-inv
SU11274
(Catalog# : 122912, Cas# :
658084-23-2
)
SU11274 is a selective Met inhibitor with IC50 of 10 nM, no effects on PGDFR, EGFR or
STF31
(Catalog# : 122831, Cas# :
724741-75-7
)
STF31 is a potent glucose transporter 1 (GLUT1).
SM-164
(Catalog# : 122802, Cas# :
957135-43-2
)
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP prot
SB-742457 ( Intepirdine )
(Catalog# : 122518, Cas# :
607742-69-8
)
SB-742457(Intepirdine) is a highly selective 5-HT6 receptor antagonist with pKi of 9.
SNG-1153
(Catalog# : 122516)
Coming soon!
SGC0946
(Catalog# : 122504, Cas# :
1561178-17-3
)
SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50
(S)-2-Ethylpiperazine dihydrochloride
(Catalog# : 122503, Cas# :
128427-05-4
)
Coming soon!
SB-505124
(Catalog# : 122502, Cas# :
694433-59-5
)
SB-505124 is a selective inhibitor of TGFR for ALK4, ALK5 with IC50 of 129 nM and 47
SP-420
(Catalog# : 122304, Cas# :
1221411-72-8
)
SP-420 is an orally active small molecule that selectively binds iron and removes it
(3S)-3-aminooxolan-2-one,hydrochloride
(Catalog# : 120804, Cas# :
2185-03-7
)
Coming soon!
Salinosporamide A
(Catalog# : 111304, Cas# :
437742-34-2
)
Salinosporamide A is a novel marine derived proteasome inhibitor which inhibits CT-L,
Sitravatinib (MGCD516)
(Catalog# : 178906, Cas# :
1123837-84-2
)
Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor tar
SB-3CT
(Catalog# : 110220, Cas# :
292605-14-2
)
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor, which is a 2-[
Spautin-1
(Catalog# : 102622, Cas# :
1262888-28-7
)
Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi