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PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
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Bromides
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Fluorides
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Indoles and Oxindoles
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
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Amino Acids
Anilines
Boronic Acids
Bromides
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Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
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Pyridines
Pyrimidines
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Name Index C
Contezolid free base
(Catalog# : 20653, Cas# :
1112968-42-9
)
Contezolid (Youxitai ®), an orally administered oxazolidinone antibacterial agent, i
CP-506 ( Synonyms: SN-36506 )
(Catalog# : 20645, Cas# :
2227304-19-8
)
CP-506 (SN-36506) is an hypoxia-activated prodrug of a DNA-alkylating nitrogen mustar
Censavudine
(Catalog# : 20632, Cas# :
634907-30-5
)
Censavudine, also known as OBP-601, BMS-986001 or festinavir, is a nucleoside reverse
CFI-402257 free base
(Catalog# : 20626, Cas# :
1610759-22-2
)
CFI-402257 was discontinued for commercial reason.
Cantharidine
(Catalog# : 20622, Cas# :
56-25-7
)
Cantharidine (free base) is a PP1/2A inhibitor found in Canarthis vesicatoria. It inh
Compound E
(Catalog# : 20575, Cas# :
209986-17-4
)
Compound E is a cell-permeable, potent, selective inhibitor of ɣ-secretase and Notch
0990CL
(Catalog# : 20562, Cas# :
511514-03-7
)
0990CL is an inhibitor of heterotrimeric Gαi subunits. 0990CL showed direct interact
CBiPES HCl
(Catalog# : 20558, Cas# :
856702-40-4
)
CBiPES HCl is a selective positive allosteric modulator of the mGlu2 receptor.
COH1 inhibitor
(Catalog# : 20555, Cas# :
20217-22-5
)
COH1 is a ribonucleotide reductase (RR) inhibitor.
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
CYM-50308
(Catalog# : 20488, Cas# :
1345858-76-5
)
CYM 50308 is a novel agonist of SIP4 (EC50 = 56 nM) that displays 37-fold selectivity
CRANAD-28
(Catalog# : 20478, Cas# :
1623747-97-6
)
CRANAD-28 is a blood brain barrier (BBB) penetrable two-photon imaging probe. It acts
CPPHA
(Catalog# : 20467, Cas# :
693288-97-0
)
CPPHA is a positive allosteric modulator of metabotropic glutamate receptor 5 (mGluR5
Camlipixant ( BLU-5937 )
(Catalog# : 20455, Cas# :
1621164-74-6
)
Camlipixant is an investigational, twice-daily oral P2X3 receptor antagonist for the
CMP3a
(Catalog# : 20441, Cas# :
647834-15-9
)
CMP3a is a NEK2 kinase inhibitor. CMP3a efficiently attenuated GBM growth in a mouse
CNS004
(Catalog# : 122622, Cas# :
695205-24-4
)
CNS004 is a novel compound that potentiates NMDA receptor currents based on glutamate
6-Chloro-4-hydroxy-[1,5]naphthyridine-3-carboxylic acid ethyl ester
(Catalog# : 20423, Cas# :
127094-58-0
)
6-chloro-4-(ethylamino)-3-Pyridinecarboxaldehyde
(Catalog# : 20418, Cas# :
959163-01-0
)
3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)pyridine hydrochloride
(Catalog# : 20408, Cas# :
1446321-95-4
)
2-(4-chlorophenyl)-2,2-difluoroacetic acid
(Catalog# : 20393, Cas# :
475301-73-6
)
2-Chloro-4'-fluoroacetophenone
(Catalog# : 20387, Cas# :
456-04-2
)
4-cyclohexyl-1,1-dimethylpiperazin-1-ium iodide
(Catalog# : G20385, Cas# :
865144-54-3
)
Cadisegliatin (TTP-399)
(Catalog# : 822225, Cas# :
859525-02-3
)
Cadisegliatin(TTP-399) is a potential liver-selective glucokinase (GK) activator for
CR8 hydrochloride
(Catalog# : L20350, Cas# :
1786438-30-9
)
CR8 is a potent and selective inhibitor of CDK. CR8 is a more potent pyridyl analogue
CCT020312
(Catalog# : L20348, Cas# :
324759-76-4
)
CCT020312 is a potent and selective EIF2AK3 Activator. CCT020312 modulates the biolog
CC-671
(Catalog# : L20343, Cas# :
1618658-88-0
)
CC-671 is a potent and selective dual inhibitor of TTK (Mps1) and CLK2.
CS-2667
(Catalog# : L20340, Cas# :
1258296-60-4
)
RO495 (CS-2667) is a potent inhibitor of Non-receptor tyrosine-protein kinase 2 (TYK2
3-cyclopropyl-7-methyl-6-nitro-2H-benzo[e][1,3]oxazin-4(3H)-one
(Catalog# : 20328, Cas# :
1038984-34-7
)
CB-103
(Catalog# : 20322, Cas# :
218457-67-1
)
CB-103 is a γ-secretase inhibitor. CB-103 inhibits Notch signaling in primary human
Cenerimod ( ACT-334441 )
(Catalog# : 20313, Cas# :
1262414-04-9
)
Cenerimod is a potent and orally active immunomodulator, exhibited EC50 value of 2.7
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add