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MAPK
Membrane Transporter/Ion Channel
Metabolism
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NF-κB
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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PROTAC
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Name Index S
S63845
(Catalog# : 171071, Cas# :
1799633-27-4
)
S63845 is a small molecule that specifically binds with high affinity to the BH3-bind
Salermide
(Catalog# : 1791511, Cas# :
1105698-15-4
)
Salermide is a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect. S
SD-06
(Catalog# : 1791320, Cas# :
271576-80-8
)
SD-06 is a MAPK p38 alpha inhibitor for the treatment of arthritis.
Sulfatinib
(Catalog# : 179135, Cas# :
1308672-74-3
)
Sulfatinib is an orally bioavailable, small molecule inhibitor of vascular endothelia
S107 HCl
(Catalog# : 1791111, Cas# :
927871-76-9
)
S107 is a Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the bi
Sematilide hydrochloride
(Catalog# : 179830, Cas# :
101526-62-9
)
Sematilide, also known as CK-1752, is a class III antiarrhythmic. It is a selective d
SNX-2112
(Catalog# : 179815, Cas# :
908112-43-6
)
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergo
SU-1498
(Catalog# : 17984, Cas# :
168835-82-3
)
SU 1498 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEG
SF2523
(Catalog# : 17918, Cas# :
1174428-47-7
)
SF2523 is a highly selective and potent dual pan-PI3K/BRD4 inhibitor. SF2523 exhibits
SAR-20347
(Catalog# : 1781101, Cas# :
1450881-55-6
)
SAR-20347 is a potent dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2).
SB756050
(Catalog# : 20178811, Cas# :
447410-57-3
)
SB-756050 is a G protein-coupled bile acid receptor 1 (GPBAR1) agonist potentially fo
SAR-405
(Catalog# : 2017882, Cas# :
1523406-39-4
)
<span style="color:#34495E;font-family:" font-size:14px;background-color
Seco Rapamycin (sodium salt)
(Catalog# : 20177313, Cas# :
148554-65-8
)
Seco-rapamycin is the first in vivo open-ring metabolite of rapamycin that does not a
SU5402
(Catalog# : 174191, Cas# :
215543-92-3
)
SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibit
SAR-020106
(Catalog# : 17031004, Cas# :
1184843-57-9
)
SAR-020106 is an ATP-competitive, potent, and selective CHK1 inhibitor with an IC50
SH5-07
(Catalog# : 17031002, Cas# :
1456632-41-9
)
SH5-07 is a robust hydroxamic acid-based STAT3 inhibitor, which induce antitumor ce
SUN11602
(Catalog# : 17030603, Cas# :
704869-38-5
)
SUN11602 is a novel aniline compound, which mimics the neuroprotective mechanisms of
Sardomozide HCl
(Catalog# : 17030306, Cas# :
138794-73-7
)
Sardomozide , also known as SAM486A or CGP48664, is a second-generation polyamine syn
Sacubitril sodium
(Catalog# : 17030108, Cas# :
149690-05-1
)
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being
SHP099 free base
(Catalog# : 17030107, Cas# :
1801747-42-1
)
SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor wi
Semagacestat
(Catalog# : 17022802, Cas# :
425386-60-3
)
Semagacestat (LY450139) is a -secretase blocker for A42, A40 and A38 with IC50 of 10.
(S)-Tedizolid
(Catalog# : 17021402, Cas# :
1431699-67-0
)
Tedizolid is the active moiety of the prodrug tedizolid phosphate, with high potency
STO-609
(Catalog# : 17021319, Cas# :
52029-86-4
)
STO-609 is a specific inhibitor of the Ca2+/Calmodulin-dependent protein kinase kina
S49076
(Catalog# : 17021309, Cas# :
1265965-22-7
)
S49076 is a novel, potent inhibitor of MET, AXL/MER, and FGFR1/2/3 with IC50 valu
SRT2183
(Catalog# : 17021306, Cas# :
1001908-89-9
)
SRT2183 is a small-molecule activator of the sirtuin subtype SIRT1, currently being
SW044248
(Catalog# : 17011714, Cas# :
522650-83-5
)
SW044248 is a potent and selective Topoisomerase I inhibitor. SW044248 killed approxi
Sugammadex sodium
(Catalog# : 17011713, Cas# :
343306-79-6
)
Sugammadex soidum is an agent for reversal of neuromuscular blockade by the agent roc
Streptozocin
(Catalog# : 17011712, Cas# :
18883-66-4
)
Streptozocin is a methylnitrosourea antineoplastic antibiotic isolated from the bacte
Sotagliflozin
(Catalog# : 17011711, Cas# :
1018899-04-1
)
Sotagliflozin, also known as LX4211, is an orally active and a dual SGLT1/SGLT2 inhib
Solithromycin
(Catalog# : 17011710, Cas# :
760981-83-7
)
Solithromycin, also known as CEM-101 and OP-1068, is a ketolide antibiotic undergoing
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
AZD0095
(Catalog# : 237072, Cas# :
2750001-23-9
)
AZD0095 is a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology.
2-MNG
(Catalog# : 24129, Cas# :
2101538-28-5
)
2-MNG is a new potent melanogenesis inhibitor, which exhibits a unique mode of action
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-