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MAPK
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index W
Wu-5
(Catalog# : 24160, Cas# :
2630378-05-9
)
Wu-5 is a USP10 inhibitor that can inhibit FLT3 and AMPK pathways, induce FLT3-ITD de
W-13 HCl
(Catalog# : 24133, Cas# :
88519-57-7
)
W-13 is a naphthalenesulfonamide derivative that acts as a potent antagonist of calmo
WM 3835
(Catalog# : 20504, Cas# :
2229025-70-9
)
WM 3835 is a lysine acetyltransferase HBO1 (KAT7) inhibitor. It reduces H3K14ac level
WK500B
(Catalog# : 20491, Cas# :
2253985-29-2
)
WK500B is a BCL6 inhibitor. WK500B engaged BCL6 inside cells, blocked BCL6 repression
WP-1130
(Catalog# : 11022, Cas# :
856243-80-6
)
Degrasyn, also known as WP1130, is a small molecule that specifically and rapidly dow
WIN54954
(Catalog# : 20280, Cas# :
107355-45-3
)
WIN54954 is a broad-spectrum antipicornavirus drug.
WAY200070
(Catalog# : 12249, Cas# :
440122-66-7
)
WAY200070 is a selective ERβ receptor agonist that displays 68-fold selectivity over
WZ-3146
(Catalog# : 19191, Cas# :
1214265-56-1
)
WZ-3146 is a covalent or irreversible pyrimidine-based EGFR inhibitor against EGFR T7
5WKS
(Catalog# : 1812252, Cas# :
1350752-07-6
)
5WKS, also known as ZINC97756584, is a biochemical.
WM-1119
(Catalog# : 181181, Cas# :
2055397-28-7
)
WM-1119 is a highly potent, selective inhibitor of lysine acetyltransferase KAT6A wit
WHI-P97
(Catalog# : 185710, Cas# :
211555-05-4
)
WHI-P97 is a JAK3 inhibitor.
WT161
(Catalog# : 184315, Cas# :
1206731-57-8
)
WT161 is a novel potent, selective, and bioavailable HDAC6 inhibitor.
WEHI-539
(Catalog# : 17101613, Cas# :
1431866-33-9
)
WEHI-539 is a highly potent and selective BCL-XL inhibitor. The pro-survival BCL-2 fa
WEHI-345
(Catalog# : 1781007, Cas# :
1354825-58-3
)
WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events
Wogonin
(Catalog# : 17031003, Cas# :
632-85-9
)
Wogonin, a natural and biologically-active flavonoid found in plants, has been report
WZ4003
(Catalog# : 17030203, Cas# :
1214265-58-3
)
WZ4003 is a selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases
1400W
(Catalog# : 17021321, Cas# :
214358-33-5
)
1400W is a slow, tight binding, and highly selective inhibitor ofinducible nitric-oxi
WWL70
(Catalog# : 16122847, Cas# :
947669-91-2
)
WWL70 is selective ABHD6 inhibitor, and it has shown anti-inflammatory and neuroprote
Wnt-C59
(Catalog# : 16122846, Cas# :
1243243-89-1
)
Wnt-C59 is a potent porcupine (PORCN) inhibitor. Wnt-C59 inhibits PORCN activity in v
WDR5-0103
(Catalog# : 16122845, Cas# :
890190-22-4
)
WDR5-0103 is a small molecule that binds a peptide-binding pocket on WDR5 (Kd = 450 n
Wnt agonist 1
(Catalog# : 16122786, Cas# :
853220-52-7
)
Wnt agonist 1 is a cell permeable Wnt signaling pathway activator, which induces -cat
WS3
(Catalog# : 16122747, Cas# :
1421227-52-2
)
WS3 is a cell proliferation inducer via modulation of Erb3 binding protein-1 (EBP1)
WNK463
(Catalog# : 6111509, Cas# :
2012607-27-9
)
WNK463 is a pan-WNK-kinase inhibitor. It potently inhibits the in vitro kinase activi
WEHI-539 hydrochloride
(Catalog# : 6111405)
WEHI-539, has high affinity (subnanomolar) and selectivity for BCL-XL and potently ki
WHI-P180 hydrochloride
(Catalog# : 611927, Cas# :
153437-55-9
)
WHI-P180 hydrochloride is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0
WAY-600
(Catalog# : 161009014, Cas# :
1062159-35-6
)
WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 n
WYE-687
(Catalog# : 1610912, Cas# :
1062161-90-3
)
WYE-687 is a potent and ATP-competitive and selective inhibitor of mTOR with IC50 of
WYE-125132
(Catalog# : 161009008, Cas# :
1144068-46-1
)
WYE-132 inhibited mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo. Im
WYE-354
(Catalog# : 1610101, Cas# :
1062169-56-5
)
WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks sig
Wortmannin
(Catalog# : 160926005, Cas# :
19545-26-7
)
It has an in vitro inhibitory concentration (IC50) of around 5 nM, making it a more p
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)