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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
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NF-κB
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index S
Senaparib
(Catalog# : 20103002, Cas# :
1401682-78-7
)
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with
SAR 131675
(Catalog# : 2091901, Cas# :
1433953-83-3
)
SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine
(1S,5R)-1-(3-fluorophenyl)-3-oxabicyclo[3.1.0]hexan-2-one
(Catalog# : 2091205, Cas# :
528587-70-4
)
SJB2-043
(Catalog# : 2071609, Cas# :
63388-44-3
)
SJB2-043 is an inhibitor of USP1 target ID1 degradation in leukemic cells.
Spastazoline
(Catalog# : 2071521, Cas# :
2351882-11-4
)
Spastazoline is a novel inhibitor for aaa+ (atpases associated with diverse cellular
SB 225002
(Catalog# : 2071510, Cas# :
18298-32-4
)
SCH-23390 maleate
(Catalog# : 2071501, Cas# :
87134-87-0
)
SCH-23390 hydrochloride is a potent dopamine receptor antagonist (Ki values are 0.2 n
((1S,2R)-1-(3-fluorophenyl)cyclopropane-1,2-diyl)dimethanol
(Catalog# : 202331, Cas# :
1369767-20-3
)
The bulk may be provided by custom synthesis.
(S)-4-(((1-Propyl-1H-imidazol-5-yl)methyl)sulfinyl)aniline
(Catalog# : 2062002, Cas# :
497223-38-8
)
SJ000291942
(Catalog# : 2051514, Cas# :
425613-09-8
)
SJ000291942 is a bone morphogenic protein (BMP) signaling activator.
Selinexor HCl
(Catalog# : 2051502, Cas# :
Unknown (HCl)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Selinexor free base
(Catalog# : 2051501, Cas# :
1393477-72-9 (free base)
)
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO
Simurosertib
(Catalog# : 2041504, Cas# :
1330782-76-7
)
Simurosertib, also known as TAK-931, is an orally bioavailable inhibitor of cell divi
SGC2085 free base
(Catalog# : 204609, Cas# :
1821908-48-8 (free base)
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
Segetalin B
(Catalog# : 204501, Cas# :
164991-89-3
)
Segetalin B is natural product isolated from Seeds of Vaccaria Segetalis. Segetalin B
S26131
(Catalog# : 112592, Cas# :
296280-56-3
)
S26131 is a bioactive chemical.
SI113
(Catalog# : 111896, Cas# :
1392816-46-4
)
SI113 is a specific inhibitor of the Sgk1 kinase activity, counteracting cancer cell
3-[(1S)-1-aminoethyl]-8-chloro-2-phenyl-1,2-dihydroisoquinolin-1-one
(Catalog# : 196301, Cas# :
1350643-72-9
)
Selisistat ( EX-527 )
(Catalog# : 52001, Cas# :
49843-98-3
)
Selisistatwas the first identified potent and cell permeable SIRT1-specific inhibitor
ST-193
(Catalog# : 193261, Cas# :
489416-12-8
)
ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, La
SPL-707
(Catalog# : 193209, Cas# :
2195361-33-0
)
SPL-707 is the first selective and orally active SPPL2a inhibitor. It shows adequate
SHP394
(Catalog# : 193122, Cas# :
2055757-40-7
)
SHP394 is a potent and orally active SHP2 inhibitor (IC50 = 23 nM) with high lipophil
SGC-GAK-1
(Catalog# : 193113, Cas# :
2226517-76-4
)
SGC-GAK-1 is a potent and selective GAK kinase probe which targets the ATP-binding si
SU 5214
(Catalog# : 19314, Cas# :
186611-04-1
)
SU 5214 is a modulator of tyrosine kinase signal transduction.
Silvestrol
(Catalog# : 192278, Cas# :
697235-38-4
)
Silvestrol, a member of flavagline family of natural products from the genus of Aglai
Selpercatinib
(Catalog# : 192276, Cas# :
2152628-33-4
)
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties.
SM16
(Catalog# : 192215, Cas# :
614749-78-9
)
SM16 is a novel Type I TGF-β signaling inhibitor.
SB-674042
(Catalog# : 192151, Cas# :
483313-22-0
)
SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat is an antineoplastic drug candidate.
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat is a rotamase inhibitor and vascular endothelial growth factor (VEGF) pro
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
AZD0095
(Catalog# : 237072, Cas# :
2750001-23-9
)
AZD0095 is a Selective Inhibitor of Monocarboxylate Transporter 4 (MCT4) for Oncology.
2-MNG
(Catalog# : 24129, Cas# :
2101538-28-5
)
2-MNG is a new potent melanogenesis inhibitor, which exhibits a unique mode of action
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-