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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
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Ordering
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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Services
Custom Synthesis
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Name Index S
SB-674042
(Catalog# : 192151, Cas# :
483313-22-0
)
SB-674042 is potent and selective OX1R antagonist. SB-674042 binds with high affinity
Seclidemstat
(Catalog# : 192147, Cas# :
1423715-37-0
)
Seclidemstat is an antineoplastic drug candidate.
Setafrastat
(Catalog# : 192146, Cas# :
1399715-48-0
)
Setafrastat is a rotamase inhibitor and vascular endothelial growth factor (VEGF) pro
Saridegib
(Catalog# : 1812251, Cas# :
1037210-93-7
)
Saridegib, also known as IPI-926, is an orally bioavailable, cyclopamine-derived inhi
SAR260301
(Catalog# : 1812134, Cas# :
1260612-13-2
)
SAR260301 is potent and selective Class I phosphatidylinositol-3-kinase (PI3K)β spec
Sparsentan
(Catalog# : 1812132, Cas# :
254740-64-2
)
Sparsentan, also known as RE-021, PS433540 and DARA-a, is a Dual angiotensin II and e
SR-0987
(Catalog# : 1810263, Cas# :
303126-97-8
)
SR-0987 is a T cell-specific RORγ (RORγt) agonist. SR-0987 induces IL-17 expression
SGC-CBP30
(Catalog# : 1810244, Cas# :
1613695-14-9
)
SGC-CBP30 is a potent and selective inhibitor of CREBBP (CBP) and EP300; which are ge
ST2825
(Catalog# : 1810243, Cas# :
894787-30-5
)
ST-2825 is MyD88 inhibitor. ST2825 provides neuroprotection after experimental trauma
Seletalisib
(Catalog# : 1810221, Cas# :
1362850-20-1
)
Seletalisib, also known as UCB-5857, is a potent and selective PI3 kinase inhibitor,
Simenepag
(Catalog# : 1810172, Cas# :
910562-15-1
)
Simenepag, also known as AGN-210676, is a small molecule prostaglandin E2 receptor ag
SR-17018
(Catalog# : 187166, Cas# :
2134602-45-0
)
SR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM.
SB-273005
(Catalog# : 186221, Cas# :
205678-31-5
)
SB-273005 is an inhibitor of integrin αvβ3.
STF-083010
(Catalog# : 185151, Cas# :
307543-71-1
)
STF-083010, also known as IRE1 Inhibitor I, is an inhibitor of the IRE1/XBP1 pathway.
SAR407899 free base
(Catalog# : 185115, Cas# :
923359-38-0
)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
SB-334867 free base
(Catalog# : 185114, Cas# :
792173-99-0
)
SB-334867 is an orexin antagonist.
SC-560
(Catalog# : 185113, Cas# :
188817-13-2
)
SC-560 is a potent, orally active and selective inhibitor of COX-1.
Seladelpar
(Catalog# : 185112, Cas# :
851528-79-5
)
Seladelpar, also known as MBX-8025 and RWJ-800025, is a selective peroxisome prolifer
SEL120-34A HCl
(Catalog# : 18574, Cas# :
1609452-30-3
)
SEL120-34A is a potent and selective CDK8 inhibitor active in AML cells with high lev
SR-4370
(Catalog# : 1842814, Cas# :
1816294-67-3
)
SR-4370 is an HDAC inhibitor.
SGC2085 HCl
(Catalog# : 184287, Cas# :
1821908-49-9
)
SGC2085 is a Potent and Selective Coactivator Associated Arginine Methyltransferase 1
S38093 HCl
(Catalog# : 184176, Cas# :
1222097-72-4
)
S38093 is an inverse agonist at histamine H3 receptors.
STO-609 acetate
(Catalog# : 184123, Cas# :
1173022-21-3
)
STO-609 is a cell-permeable inhibitor of calcium/calmodulin-dependent kinase kinases
Super-TDU
(Catalog# : 18495, Cas# :
1599441-71-0
)
Super-TDU is an inhibitory polypeptide targeting yap-teads interaction.
SSD114 HCl
(Catalog# : 18427, Cas# :
N/A
)
SSD114 is a GABAB positive allosteric modulator. SSD114 potentiated GABA-stimulated [
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)methyl 2,4-dimethylbenzoate
(Catalog# : 183219, Cas# :
1253955-19-9
)
(S)-(4-(3-(tert-butoxycarbonyl)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)phenyl)met
(S)-3-(tert-butoxycarbonyl)-2-(4-((2,4-dimethylbenzoyloxy)methyl)phenyl)propanoic acid
(Catalog# : 183218, Cas# :
2097334-20-6
)
(S)-3-(tert-butoxycarbonyl)-2-(4-((2,4-dimethylbenzoyloxy)methyl)phenyl)propanoic aci
(S)-Butyl 2-hydroxybutanoate
(Catalog# : 1712291, Cas# :
132513-51-0
)
butyl (2S)-2-hydroxybutanoate is building blocks.
SCR7 pyrazine
(Catalog# : 1712261, Cas# :
14892-97-8
)
SCR7 pyrazine is a small molecule inhibitor of DNA ligase IV that prevents nonhomolog
S38093
(Catalog# : 17101615, Cas# :
862896-30-8
)
S 38093 is a brain-penetrant antagonist of H3 receptor, with Ki of 8.8, 1.44 and 1.2
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).