EA1080 (Synonyms: NSHO-101)
Catalog No: 26A098
CAS Number: 2122780-15-6
Purity: ≧98.0%
Emvistegrast (GS-1427) is an investigational oral α4β7 integrin inhibitor.
For research use only. We do not sell to patients.
Chemical Information
| Name | EA1080 (Synonyms: NSHO-101) |
|---|---|
| Iupac Chemical Name | isobutyl (S)-2-(2,5-difluoro-4-((4-pivalamidophenyl)sulfonamido)benzamido)-3-(6-(3,4-dimethyl-2,6-dioxo-3,6-dihydropyrimidin-1(2H)-yl)pyridin-3-yl)propanoate |
| Synonyms | EA1080; NSHO-101; NSHO101; NSHO 101; EA-1080; EA 1080 |
| Molecular Formula | C36H40F2N6O8S |
| Molecular Weight | 754.81 |
| Smile | O=C(C(C)(C)C)NC1=CC=C(S(NC2=CC(F)=C(C(N[C@@H](CC3=CN=C(N4C(N(C)C(C)=CC4=O)=O)C=C3)C(OCC(C)C)=O)=O)C=C2F)(=O)=O)C=C1 |
| InChiKey | QKDMZJAVMPLEAL-LJAQVGFWSA-N |
| InChi | InChI=1S/C36H40F2N6O8S/c1-20(2)19-52-33(47)29(15-22-8-13-30(39-18-22)44-31(45)14-21(3)43(7)35(44)49)41-32(46)25-16-27(38)28(17-26(25)37)42-53(50,51)24-11-9-23(10-12-24)40-34(48)36(4,5)6/h8-14,16-18,20,29,42H,15,19H2,1-7H3,(H,40,48)(H,41,46)/t29-/m0/s1 |
| CAS Number | 2122780-15-6 |
| Related CAS | 2122780-15-6 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | α4β7 integrin inhibitor |
|---|---|
| Mechanism | α4β7 integrin inhibitor |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
