Ontunisertib (Synonyms: AGMB-129)
Catalog No: 26A096
CAS Number: 2647949-48-0
Purity: ≧98.0%
Ontunisertib (also known as AGMB-129) is an investigational, oral, gastrointestinal-restricted small molecule inhibitor of ALK5 (TGFβ receptor 1).
For research use only. We do not sell to patients.
Chemical Information
| Name | Ontunisertib (Synonyms: AGMB-129) |
|---|---|
| Iupac Chemical Name | N-(2,6-Difluorobenzyl)-2-(3-(6-methylpyridin-2-yl)-4-(quinolin-4-yl)-1H-pyrazol-1-yl)acetamide |
| Synonyms | Ontunisertib; AGMB-129; AGMB129; AGMB 129. |
| Molecular Formula | C27H21F2N5O |
| Molecular Weight | 469.50 |
| Smile | O=C(NCC1=C(C=CC=C1F)F)CN2N=C(C3=CC=CC(C)=N3)C(C4=C5C=CC=CC5=NC=C4)=C2 |
| InChiKey | QGXRIRYULXOGDQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H21F2N5O/c1-17-6-4-11-25(32-17)27-21(18-12-13-30-24-10-3-2-7-19(18)24)15-34(33-27)16-26(35)31-14-20-22(28)8-5-9-23(20)29/h2-13,15H,14,16H2,1H3,(H,31,35) |
| CAS Number | 2647949-48-0 |
| Related CAS | 2647949-48-0 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | TGFβ receptor 1 |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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