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Angiogenesis
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Autophagy
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GPCR & G Protein
Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index B
Bezuclastinib
(Catalog# : 25198, Cas# :
1616385-51-3
)
Bezuclastinib is an oral, small-molecule inhibitor of the kinase activity of the KIT
Bexobrutideg ( NX-5948 )
(Catalog# : 25197, Cas# :
2649400-34-8
)
Bexobrutideg (NX-5948) is a BTK degrader.
BMS-986299
(Catalog# : 25169, Cas# :
2242952-69-6
)
MS-986299 is a NLRP3 inflammasome agonist.
BMS-986458
(Catalog# : 25132, Cas# :
3005272-36-3
)
Bisantrene HCl
(Catalog# : 25122, Cas# :
71439-68-4
)
Bisantrene, aslo known as CL-216942 and NSC 337766, is topoisomerase II poisons and D
BMS-986449
(Catalog# : 25119)
BMS-986449 is a CELMoD molecular glue that redirects the E3 ubiquitin ligase Cereblon
BBC0403
(Catalog# : 25058, Cas# :
2644662-83-7
)
BBC0403 is a selective BRD2 inhibitor. BBC0403 inhibits the progression of osteoarthr
BAY-593 free base
(Catalog# : 25055, Cas# :
2413020-56-9
)
BAY-593 is an orally active inhibitor of geranylgeranyltransferase-I (GGTase-I) that
BAY-1125976
(Catalog# : 25048, Cas# :
1402608-02-9
)
BAY-1125976 is a potent and selective allosteric AKT1/2 inhibitor. BAY-1125976 exhibi
BMS-466442
(Catalog# : 25032, Cas# :
1598424-76-0
)
BMS-466442 is a small molecule inhibitor of asc-1.
BTA-EG4 hydrate
(Catalog# : 24157, Cas# :
921193-28-4
)
BTA-EG4 is a catalase-amyloid interaction inhibitor, which can significantly enhance
Bexicaserin
(Catalog# : 24117, Cas# :
2035818-24-5
)
Bexicaserin is a serotonin 5-HT2C receptor agonist.
BIIB-129
(Catalog# : 24086, Cas# :
2770961-85-6
)
4-Bromoindole-3-carboxaldehyde
(Catalog# : 24059, Cas# :
98600-34-1
)
Braco-19 trihydrochloride
(Catalog# : 24034, Cas# :
351351-75-2
)
Braco-19 is a potenttelomerase/telomereinhibitor, preventing the capping and catalyti
BIIB-129
(Catalog# : 24025, Cas# :
2770960-52-4
)
BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine k
BLU-451
(Catalog# : 20668, Cas# :
2769954-39-2
)
BLU-451, also known as LNG-451, orally bioavailable, central nervous system (CNS) pen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
Brexpiprazole
(Catalog# : 20620, Cas# :
913611-97-9
)
Brexpiprazole, also known as OPC-34712, is a novel D2 dopamine partial agonist called
Berotralstat HCl
(Catalog# : 20619, Cas# :
1809010-52-3
)
Berotralstat HCl is a novel selective inhibitor of plasma kallikrein, blocking the en
Belzutifan
(Catalog# : 20606, Cas# :
1672668-24-4
)
Belzutifan, also known as PT2977 and MK-6482, is HIF-2alpha inhibitor. PT2977 binds t
BI-1467335 HCl
(Catalog# : 20601, Cas# :
1478364-68-9
)
BI-1467335, also known as PXS-4728A, is a SSAO/VAP inhibitor potentially for the trea
Bozitinib
(Catalog# : 20599, Cas# :
1440964-89-5
)
Bozitinib is a highly selective c-MET kinase inhibitor with blood-brain barrier perme
BMS-986176
(Catalog# : 20597, Cas# :
1815613-42-3
)
BMS-986176, also known as LX9211, is a highly selective, CNS penetrant, potent AAK1 i
BBT
(Catalog# : 20570, Cas# :
445000-45-3
)
BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS).
BML-278
(Catalog# : 20554, Cas# :
120533-76-8
)
BML-278 is an activator of sirtuin 1 (SIRT1) that has an EC150 value (effective conce
BSJ-04-122
(Catalog# : 20550, Cas# :
2513289-74-0
)
brigimadlin
(Catalog# : 20533, Cas# :
2095116-40-6
)
Brigimadlin is an E3 ubiquitin-protein ligase Mdm2 inhibitor with potential as an ant
BMS-986120
(Catalog# : 20519, Cas# :
1478712-37-6
)
BMS-986120 is a potent and selective oral antagonist of protease-activated receptor-4
BMS-986141
(Catalog# : 20518, Cas# :
1478711-48-6
)
BMS-986141 is an Orally-Active Small-Molecule Antagonist of the Platelet Protease-Act
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran