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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
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GPCR & G Protein
Metabolism
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Bromides
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Chiral Compounds
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Fluorides
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Indoles and Oxindoles
Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index S
Sotuletinib HCl
(Catalog# : 20663, Cas# :
2222138-31-8 (HCl)
)
Sotuletinib, also known as BLZ945, is a potent and selective CSF-1R kinase inhibitor.
SKF-91488 HCl
(Catalog# : 20662, Cas# :
68941-21-9
)
SKF 91488 dihydrochloride is a homolog of dimaprit.
Sonrotoclax
(Catalog# : 20650, Cas# :
2383086-06-2
)
Sonrotoclax is an antineoplastic.
SOP1812 (QN-302)
(Catalog# : 20639, Cas# :
2546091-70-5
)
QN-302 is a G-quadruplex (G4)-selective transcription inhibitor.
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is an allosteric PI3Kα inhibitor that selectively targets prevalent PI3Kα h
SEW2871
(Catalog# : 20604, Cas# :
256414-75-2
)
SEW2871 is a S1P1 agonist (sphingosine-1-phosphate type 1 receptor agonist). SEW2871
STX-721
(Catalog# : 20576, Cas# :
2765525-82-2
)
STX-721 is a next-generation, orally delivered therapy, designed with potential best-
STC-15
(Catalog# : 20549, Cas# :
2648257-56-9
)
STC-15 is a first-in-class inhibitor of RNA modification and is the first ever RNA me
(S)-1-BOC-2-METHYL-[1,4]DIAZEPANE
(Catalog# : 20541, Cas# :
194032-32-1
)
(S)-5-fluoro-3-methylbenzo[c][1,2]oxaborol-1(3H)-ol
(Catalog# : 20522, Cas# :
2921961-53-5
)
(S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
(Catalog# : 20516, Cas# :
131690-60-3
)
Samidorphan
(Catalog# : 20454, Cas# :
852626-89-2
)
Samidorphan, also known as ALKS-33 and RDC-0313, is an opioid modulator with μ-antag
Spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidine]-7'(8'H)-carboxylic acid, 2'-(methylthio)-6'-oxo-5'-[[(trifluoromethyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
(Catalog# : 20412, Cas# :
2170746-98-0
)
(S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine
(Catalog# : 20396, Cas# :
1980023-96-8
)
SB-4 agonist
(Catalog# : G20378, Cas# :
100874-08-6
)
SB 4 is a potent BMP4 agonist.
SEP-363856 HCl ( SEP-856 )
(Catalog# : 822222, Cas# :
1310422-41-3 (HCl)
)
SEP-363856 is a novel trace amine receptor 1 (TAAR1) agonist with serotonin 5-HT1A ac
SRI-37330 free base
(Catalog# : 1711224, Cas# :
2322245-42-9 (free base)
)
SRI-37330 is a novel inhibitor of TXNIP expression, decreasing glucagon secretion and
Sunvozertinib ( DZD 9008 )
(Catalog# : 20369, Cas# :
2370013-12-8
)
Sunvozertinib, also known as DZD9008, is an oral, potent, irreversible, and selective
SHMT-IN-2
(Catalog# : 20368, Cas# :
2102681-49-0
)
SHMT-IN-2 is a serine hydroxymethyltransferase (SHMT) inhibitor, potently inhibiting
SRI-011381
(Catalog# : L20355, Cas# :
1629138-41-5
)
SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer
SJ-172550
(Catalog# : L20353, Cas# :
431979-47-4
)
SJ-172550, also known as MDMX Inhibitor II, is an inhibitor of MDMX that disrupts MDM
SMN-C3
(Catalog# : 20344, Cas# :
1449597-34-5
)
SMN-C3is an orally active SMN2 splicing modulator and has the potential to treat spin
Stafia-1
(Catalog# : L20338, Cas# :
2582757-90-0
)
STM2457
(Catalog# : 20321, Cas# :
2499663-01-1
)
STM2457 is a highly potent and selective first-in-class catalytic inhibitor of METTL3
SRI-37330 HCl
(Catalog# : 20306, Cas# :
2322245-49-6
)
SRI-37330 hydrochloride is a novel inhibitor of TXNIP expression,and dose-dependently
SM-102
(Catalog# : 21252, Cas# :
2089251-47-6
)
SM-102 is an ionizable amino lipid that has been used in combination with other lipid
Seralutinib
(Catalog# : 21238, Cas# :
1619931-27-9
)
Seralutinib, also known as PK-10571 and GB002, is a Novel Inhaled Pdgfr Kinase Inhibi
Sonidegib (LDE-225)
(Catalog# : 21232, Cas# :
956697-53-3
)
Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable
SB-366791
(Catalog# : 21230, Cas# :
472981-92-3
)
SB-366791 is a potent and selective TRPV1 antagonist. SB-366791 inhibits glutamatergi
Scriptaid
(Catalog# : 21229, Cas# :
287383-59-9
)
Scriptaid, also known as GCK 1026, is a HDAC inhibitor. Scriptaid protects against tr
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).