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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
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Boronic Acids
Bromides
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Deuterated
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Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Name Index H
HDM-2006 ( Synonyms: DD205-291)
(Catalog# : 25163)
HDM-2006 (DD-205-291) is a a novel PROTAC-based HPK1 degrader with High Potency and S
HQ461
(Catalog# : 25162, Cas# :
1226443-41-9
)
HQ461 is a Molecular-glue degrader. HQ461 acts by promoting an interaction between CD
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
1H-Indazole, 6-bromo-1,3-dimethyl-
(Catalog# : 25036, Cas# :
1095539-84-6
)
HC-5404
(Catalog# : 25001, Cas# :
2247396-91-2
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
H2-Gamendazole
(Catalog# : 24145, Cas# :
877768-84-8
)
H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycysti
HTL14242
(Catalog# : 24115, Cas# :
1644645-32-8
)
HTL14242 is a mGlu5 Negative Allosteric Modulator. Metabotropic glutamate receptors (
HC-5404-FU
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404-FU is a novel, highly selective and potent PERK inhibitor.
HH-0043
(Catalog# : 24077, Cas# :
2922069-42-7
)
HFY-4A
(Catalog# : 20661, Cas# :
2094810-82-7
)
HFY-4A is a HDAC inhibitor. HFY-4A inhibits breast cancer cell proliferation, migrati
Hynic-TOC
(Catalog# : 20658, Cas# :
257943-19-4
)
Hynic-TOC is a ligand for making 99mTc-Hynic-TOC as an imaging agent in the diagnosti
HDAC-IN-58
(Catalog# : 20568, Cas# :
2071224-39-8
)
HDAC-IN-58 is a HDAC inhibitor.
1H-1,2,3-triazole, 4,5-diiodo-
(Catalog# : 20521, Cas# :
28194-09-4
)
HM43239
(Catalog# : 20517, Cas# :
2569527-64-4
)
HM43239 is an orally active small molecule inhibitor of FLT3 that selectively inhibit
4(3H)-Pyrimidinone, 5-bromo-6-cyclopropyl-
(Catalog# : 20482, Cas# :
27192-20-7
)
2(1H)-Pyridinone, 5,6-dihydro-4-(4-methylphenyl)-3-(2H-tetrazol-5-yl)-6-[4-(4,4,4-trifluorobutoxy)phenyl]-6-(trifluoromethyl)-, (6S)-
(Catalog# : 20430, Cas# :
1441057-15-3
)
1H-Indazole-1-acetic acid, 3-acetyl-5-bromo-, 1,1-dimethylethyl ester
(Catalog# : 20422, Cas# :
2086183-72-2
)
1H-Pyrrolo[2,3-b]pyridine, 4-chloro-1-[tris(1-methylethyl)silyl]-
(Catalog# : 20410, Cas# :
651744-48-8
)
4-hydroxybiphenyl-4-carboxamide
(Catalog# : 20404, Cas# :
182318-78-1
)
1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, ethyl ester
(Catalog# : 20388, Cas# :
221675-35-0
)
6-Hydroxyl-2-tetralone
(Catalog# : 20371, Cas# :
52727-28-3
)
HISPOLON(P)
(Catalog# : 210201, Cas# :
173933-40-9
)
5-Hydroxymethyldeoxyuridine
(Catalog# : 2091910, Cas# :
5116-24-5
)
5-Hydroxymethyldeoxyuridine is a nucleoside analog with anticancer and antiviral acti
5-hydroxy-2,4-dimethylpyrimidine
(Catalog# : 2091204, Cas# :
412003-95-3
)
2,4-dimethylpyrimidin-5-ol is a key intermidiate ofLemborexant. Kg scale may be provi
H-BETA-ALA-AMC TFA
(Catalog# : 2071633, Cas# :
201847-54-3
)
HC-070
(Catalog# : 206104, Cas# :
1628291-95-1
)
HC-070 is a potent inhibitor of TRPC4 and TRPC5, leading to anxiolytic and antidepres
Hydroxyfasudil HCl
(Catalog# : 204610, Cas# :
155558-32-0 (HCl)
)
Hydroxyfasudil, aslo known as HA1100, is a cell-permeable hydroxylated metabolite of
HBX-41108
(Catalog# : 19317, Cas# :
924296-39-9
)
HBX 41108 is an inhibitor of ubiquitin-specific protease (USP) 7. HBX 41108 inhibits
HS-1371
(Catalog# : 192223, Cas# :
2158197-70-5
)
HS-1371 is a novel kinase inhibitor of RIP3-mediated necroptosis. HS-1371 directly bi
HZ-1157
(Catalog# : 19182, Cas# :
1009734-33-1
)
HZ-1157 is a hepatitis C virus (HCV) inhibitor with inhibitory activities toward HCV
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MTX115325
(Catalog# : 186264, Cas# :
2750895-97-5
)
MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with good drug-like
LY-3381916
(Catalog# : 193123, Cas# :
2166616-75-5
)
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, bi
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
CAY 10566
(Catalog# : 10403, Cas# :
944808-88-2
)
CAY 10566 is a potent selective SCD-1 inhibitor.
Cadefrecitinib (GLPG-3667)
(Catalog# : 20509, Cas# :
2308520-97-8
)
Cadefrecitinib (GLPG-3667) is an oral, small molecule inhibitor of the TYK2 kinase in
QBS10072S
(Catalog# : 25190, Cas# :
1802735-28-9
)
QBS10072S isa blood-brain-barrier (BBB) penetrative agent composed of a cytotoxic che
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes