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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
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Name Index N
NSD1 inhibitor BT5
(Catalog# : 25207, Cas# :
2351225-46-0
)
BT5 potently inhibits NSD1, engages the SET domain in cells, and reduces H3K36me2 lev
Nizubaglustat ( Synonyms: AZ-3102 )
(Catalog# : 25175, Cas# :
1633666-49-5
)
Nizubaglustat (AZ-3102) is an oral small molecule which inhibits glucosylceramide syn
NT-0796
(Catalog# : 25153, Cas# :
2272917-13-0
)
NT-0796 is an oral small molecule which inhibits NLRP3 inflammasome.
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
Nedisertib ( peposertib )
(Catalog# : 25094, Cas# :
1637542-33-6
)
Nedisertib, also known as M-3814, MSC2490484A, is an orally available inhibitor of DN
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
NT219
(Catalog# : 25067, Cas# :
1198078-60-2
)
NT219 is a novel inhibitor of the insulin/igf signaling cascade (iis), mediating a lo
Nanatinostat
(Catalog# : 25034, Cas# :
1256448-47-1
)
Nanatinostat, also known as Tractinostat, CHR-3996 and VRx-3996, is an orally bioavai
NPD-3519
(Catalog# : 24089, Cas# :
3032452-90-4
)
NDI-091143
(Catalog# : 24057, Cas# :
2375840-87-0
)
NDI-091143 is a novel potent inhibitor of human ATP-citrate lyase, indirectly disrupt
NMD670
(Catalog# : 24050, Cas# :
2354321-33-6
)
NMD670 is an orally bioavailable skeletal muscle-specific chloride ion channel (ClC-1
NNC-55-0396
(Catalog# : 24038, Cas# :
357400-13-6
)
NNC-55-0396 is a highly selective T-type calcium channel blocker which can be used fo
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add
Navacaprant ( BTRX-335140 )
(Catalog# : 23122601, Cas# :
2244614-14-8
)
Navacaprant (NMRA-335140, BTRX-140) is an oral, selective, reversible, small-molecule
Ninerafaxstat
(Catalog# : 20608, Cas# :
2254741-41-6
)
Ninerafaxstat is a biochemical that decreases fatty acid oxidation and improves mitoc
NBI-921352
(Catalog# : 20602, Cas# :
2154406-04-7
)
NBI-921352 is a potent, highly selective Nav1.6 sodium channel inhibitor being develo
Navitoclax-piperazine
(Catalog# : 20559, Cas# :
2143096-93-7
)
Navitoclax-piperazine, also known as ABT-263-piperazine, is a Navitoclax derative and
NMS-293 ( NMS-P293 )
(Catalog# : 20514, Cas# :
1606996-12-6
)
NMS-293 is a PARP-1 inhibitor in early clinical development at Nerviano Medical Scien
NSC348884
(Catalog# : 20487, Cas# :
81624-55-7
)
NSC348884 is a nucleophosmin inhibitor. NSC348884 also disrupts oligomer formation an
NSC-92828
(Catalog# : 20486, Cas# :
13728-56-8
)
NSC-92828, also known as 3-Phenanthrenebutyric acid, is a Protein–protein interacti
NSC-45586
(Catalog# : 20483, Cas# :
6300-44-3
)
NSC-45586 is a pan-PHLPP inhibitor selective for PHLPP1 and PHLPP2.
NXP-800 ( CCT361814 )
(Catalog# : 233141, Cas# :
1693734-80-3
)
NXP800 is an oral small molecule inhibitor of the Heat Shock Factor 1 (HSF1) pathway.
NBD-14270
(Catalog# : 20448, Cas# :
2411819-82-2
)
NXY-059 ( Disufenton Sodium )
(Catalog# : 52014, Cas# :
168021-79-2
)
NXY-059 ( Disufenton Sodium ) is a disulfonyl derivative of phenyl-tert-butyl nitrone
N-Benzyl-2,6-difluoro-3,5-dimethoxyaniline
(Catalog# : 20411, Cas# :
651734-53-1
)
N-(6-bromo-2-ethyl-8-methylimidazo[1,2-a]pyridin-3-yl)formamide
(Catalog# : 20402, Cas# :
1628263-77-3
)
N-(6-bromo-2-ethyl-8-methylimidazo[1,2-a]pyridin-3-yl)-N-methylformamide
(Catalog# : 20401, Cas# :
1628263-96-6
)
N,N-DIETHYL-2,6-CIS-DIMETHYLPIPERIDINIUM IODIDE
(Catalog# : G20383, Cas# :
1335241-44-5
)
Navoximod free base
(Catalog# : 20290, Cas# :
1402837-78-8 (free base)
)
NE 52-QQ57
(Catalog# : 21233, Cas# :
1401728-56-0
)
NE52-QQ57 is an orally available GPR4 antagonist with an IC50 of 70 nM. NE 52-QQ57 si
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007 is a selective and brain-penetrant inhibitor of acetyl CoA synthase 2 (ACSS2).
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444 is an anti-cancer agent by inhibiting PC ( pyruvate carboxylase ) activity.
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584 is a novel brain-permeable ACSS2 inhibitors.
IDB-003
(Catalog# : 26A017, Cas# :
3079716-11-0
)
IDB-003 inhibits MDA-MB-231 tumor growth in vivo.
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)