SMER28
Catalog No: 17011709
CAS Number: 307538-42-7
Purity: 98%
SMER28 is a small molecule modulator of autophagy, inducing autophagy independently of rapamycin in mammalian cells. SMER28, acting via an mTOR-independent mechanism, prevented the accumulation of amyloid beta peptide within these cells. SMER28 may have therapeutic potential for the treatment of Alzheimer's disease and other proteinopathies.
For research use only. We do not sell to patients.
Chemical Information
| Name | SMER28 |
|---|---|
| Iupac Chemical Name | 6-bromo-N-2-propen-1-yl-4-quinazolinamine |
| Synonyms | SMER-28; SMER 28 |
| Molecular Formula | C11H10BrN3 |
| Molecular Weight | 264.126 |
| Smile | BrC=1C=C2C(=NC=NC2=CC1)NCC=C |
| InChiKey | BCPOLXUSCUFDGE-UHFFFAOYSA-N |
| InChi | InChI=1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15) |
| CAS Number | 307538-42-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
