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Solithromycin

Catalog No.: 17011710
Cas No.: 760981-83-7
Purity : 98% 
17011710 - Solithromycin | CAS 760981-83-7

Catalog number : 17011710

CAS number : 760981-83-7

Molecular Formula : C43H65FN6O10 

Molecular Weight : 845.01 

Iupac Chemical Name : (3aS,4R,7R,9R,10R,11R,13R,15S,15aR)-1-(4-(4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl)butyl)-10-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-ethyl-7-fluoro-11-methoxy-3a,7,9,11,13,15-hexamethyloctahydro-1H-[1]oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(7H,9H)-tetraone 

Smile : NC=1C=C(C=CC1)C=1N=NN(C1)CCCCN1C(O[C@]2([C@H]1[C@@H](C([C@@H](C[C@@]([C@@H]([C@H](C([C@@](C(O[C@@H]2CC)=O)(C)F)=O)C)O[C@@H]2O[C@@H](C[C@@H]([C@H]2O)N(C)C)C)(C)OC)C)=O)C)C)=O

InChiKey : IXXFZUPTQVDPPK-QIFQIIIXSA-N

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SynonymsCEM101; CEM101; CEM 101; OP1068; OP1068; OP 1068 
Molecular FormulaC43H65FN6O10 
Molecular Weight845.01 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileNC=1C=C(C=CC1)C=1N=NN(C1)CCCCN1C(O[C@]2([C@H]1[C@@H](C([C@@H](C[C@@]([C@@H]([C@H](C([C@@](C(O[C@@H]2CC)=O)(C)F)=O)C)O[C@@H]2O[C@@H](C[C@@H]([C@H]2O)N(C)C)C)(C)OC)C)=O)C)C)=O
InChiKeyIXXFZUPTQVDPPK-QIFQIIIXSA-N
InChiInChI=1S/C43H65FN6O10/c1-12-32-43(8)35(50(40(55)60-43)19-14-13-18-49-23-30(46-47-49)28-16-15-17-29(45)21-28)26(4)33(51)24(2)22-41(6,56-11)37(27(5)36(53)42(7,44)39(54)58-32)59-38-34(52)31(48(9)10)20-25(3)57-38/h15-17,21,23-27,31-32,34-35,37-38,52H,12-14,18-20,22,45H2,1-11H3/t24-,25-,26-,27+,31+,32-,34-,35-,37-,38+,41-,42-,43-/m1/s1
Coming soon.
Solithromycin, also known as CEM-101 and OP-1068, is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections. It is expected to be the first macrolide antibiotic available in intravenous, oral, and pediatric suspension formulations in over 20 years. Solithromycin exhibits excellent in vitro activity against a broad spectrum of Gram-positive respiratory tract pathogens, including macrolide-resistant strains. Solithromycin has activity against a wide variety of pathogens, and further research is being conducted for other infections. 

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