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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Bromides
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
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Name Index L
Lorundrostat
(Catalog# : 20654, Cas# :
1820940-17-7
)
Lorundrostat is an aldosterone synthase inhibitor.
LEO-32731
(Catalog# : 20625, Cas# :
1353546-86-7
)
LEO-32731 is a bioactive chemical.
Losmapimod
(Catalog# : 20588, Cas# :
585543-15-3
)
Losmapimod, also know as GW856553 or GW856553X or GSK-AHAB, is a drug developed by Gl
LY3522348
(Catalog# : 20577, Cas# :
2568608-48-8
)
Lin281632
(Catalog# : 20551, Cas# :
108825-65-6
)
Lin28 1632, is a RNA binding protein Lin28 inhibitor. Lin281632 promotes mESC differe
LUNA18
(Catalog# : 20531, Cas# :
unknown
)
LUNA18 is a N-alkyl-rich cyclic peptide
LQZ-7I
(Catalog# : 20477, Cas# :
195822-23-2
)
LQZ-7I is a malarial protease PfSUB1 inhibitor. LQZ-7I showed significantly improved
LSN2463359
(Catalog# : 20461, Cas# :
1401031-52-4
)
LSN2463359 is a novel positive allosteric modulators of the mGlu₅ receptor.
LFM-A13
(Catalog# : 20438, Cas# :
244240-24-2
)
LFM-A13 is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK). LF
Linzagolix
(Catalog# : 20266, Cas# :
935283-04-8
)
Linzagolix is a novel, orally administered GnRH receptor antagonist that potentially
LY-3475070
(Catalog# : 21244, Cas# :
2375815-63-5
)
LY-3475070 is a potent and selective CD73 Inhibitor with IC50 of 28 nM. LY3475070 Alo
LP-261
(Catalog# : 210507, Cas# :
915412-67-8
)
LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine sit
LM11A-31 HCl
(Catalog# : 21225, Cas# :
1243259-19-9
)
LVN84663
(Catalog# : 20113001, Cas# :
103784-66-3
)
LVN84663 is a useful reagent for determination of blood coagulating protease. It was
LUN42518
(Catalog# : 2091908, Cas# :
47142-51-8
)
LUN42518, also known as Phentolamine Analogue 1, is an analogue of phentolamine. Phen
Lerociclib HCl (G1T38 HCl)
(Catalog# : 2073106, Cas# :
2097938-59-3
)
Lerociclib HCl (G1T38)is a novel, selective,differentiated oral CDK4/6 inhibitor with
Lobaplatin
(Catalog# : 2071555, Cas# :
135558-11-1
)
Lobaplatin (D-19466) is a diastereometric mixture of platinum(II) complexes containin
Lixivaptan
(Catalog# : 2071524, Cas# :
168079-32-1
)
Lixivaptan, laso known as CRTX-080; VPA-985; WAY-VPA-985, is a potent, orally active,
LAU159
(Catalog# : 2071505, Cas# :
2055050-87-6
)
LAU159 is a potent modulator of α6β3γ2 GABAA receptor.
Lificiguat
(Catalog# : 2071502, Cas# :
170632-47-0
)
Lificiguat, also known as YC-1, is a inhibitor of Hypoxia-inducible factor-1alpha (HI
Lanraplenib
(Catalog# : 20732, Cas# :
1800046-95-0
)
Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor in develo
Linperlisib free base
(Catalog# : 2061309, Cas# :
1702816-75-8
)
Linperlisib, also known as YY-20394 and PI3Kδ-IN-2, is a potent and selective PI3Kδ
L006235
(Catalog# : 2061307, Cas# :
294623-49-7
)
L006235 is a potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays
LML-134
(Catalog# : 2051510, Cas# :
1542135-76-1
)
LML134 is an orally active and high selective Histamine 3 receptor (H3R) inverse agon
LUT-014
(Catalog# : 2042701, Cas# :
2274819-46-2
)
LUT-014 is a B-Raf Inhibitor. Leveraging the paradoxical effect of B-Raf Inhibitors,
LSZ102
(Catalog# : 2041502, Cas# :
2135600-76-7
)
LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50
LUN42589
(Catalog# : 204502, Cas# :
1848242-58-9
)
LUN42589, also known as PI3K/mTOR Inhibitor-2, is a potent dual pan-PI3K/mTOR inhibit
Lerociclib
(Catalog# : 204302, Cas# :
1628256-23-4 (free base)
)
Lerociclib , also known as G1T38, is an oral, potent and selective CDK4/6 inhibitor f
Lemborexant (E-2006)
(Catalog# : 6111904, Cas# :
1369764-02-2
)
Lemborexant(CAS 1369764-02-2)is a novel investigational small molecule that inhib
LY2794193
(Catalog# : 193262, Cas# :
2173037-97-1
)
LY2794193 is a highly potent and selective mGlu3 receptor agonist.
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).
NVL-655 ( ALK-IN-27 )
(Catalog# : 24003, Cas# :
2739866-40-9
)
NVL-655 is a novel, brain-penetrant, ALK-selective inhibitor that was designed to add