Engasertib (previously known as ALM 301) is a small molecule, selective allosteric AKT inhibitor.
For research use only. We do not sell to patients.
| Name | Engasertib (Synonyms: ALM301) |
|---|---|
| Iupac Chemical Name | 6-(4-((1s,3s)-1-amino-3-hydroxycyclobutyl)phenyl)-1-ethyl-7-phenyl-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one |
| Synonyms | Engasertib; ALM301; ALM 301; ALM-301 |
| Molecular Formula | C25H25N3O3 |
| Molecular Weight | 415.49 |
| Smile | N[C@@]1(C[C@H](O)C1)C2=CC=C(C(N=C(OCC3=O)C(N3CC)=C4)=C4C5=CC=CC=C5)C=C2 |
| InChiKey | BPHCAPAOSHZYJY-KJDSRRNHSA-N |
| InChi | InChI=1S/C25H25N3O3/c1-2-28-21-12-20(16-6-4-3-5-7-16)23(27-24(21)31-15-22(28)30)17-8-10-18(11-9-17)25(26)13-19(29)14-25/h3-12,19,29H,2,13-15,26H2,1H3/t19-,25+ |
| CAS Number | 1313439-71-2 |
| Related CAS | 1313439-71-2 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | AKT inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |