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Inhibitors & Agonists
Angiogenesis
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Autophagy
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DNA Damage
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GPCR & G Protein
Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index Y
YTX-465
(Catalog# : 24139, Cas# :
2225824-53-1
)
YTX-465 is a SCD inhibitor. YTX-465 strongly reduced fatty desaturation in a concentr
YCT529
(Catalog# : 24120, Cas# :
2863670-67-9
)
YCT529, an RAR-α inhibitor, is used as a contraceptive, with a 99% effectiveness. YC
YK-029A
(Catalog# : 20670, Cas# :
2064269-82-3
)
YW2065
(Catalog# : 20494, Cas# :
2131223-85-1
)
YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achi
YKL-05-099
(Catalog# : 21241, Cas# :
1936529-65-5
)
YKL-05-099 is a selective inhibitor of Salt-Inducible Kinase (SIK).
YCN47284
(Catalog# : 2073105, Cas# :
181147-28-4
)
YCN47284 is an aromatic guanylhydrazone compounds with antimalarial activity.
YUN27078
(Catalog# : 2071610, Cas# :
879127-07-8
)
YUN27078, also known as EGFR inhibitor, is an EGFR inhibitor. It directly depolymeriz
Y06137
(Catalog# : 193193, Cas# :
2226534-49-0
)
Y06137 is a potent and selective BET inhibitor, which binds to the BRD4(1) bromodomai
YF-2 hydrochloride
(Catalog# : 193151, Cas# :
1312005-62-1
)
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acety
YH239-EE
(Catalog# : 192213, Cas# :
1364488-67-4
)
YH239-EE is a highly potent p53-MDM2 antagonist.
Y-39983 free base
(Catalog# : 185172, Cas# :
199433-58-4
)
Y-39983 (free base), also known as Y-33075, is a potent and selective inhibitor of RO
YL-0919
(Catalog# : 18578, Cas# :
1339058-04-6
)
YL-0919 is a novel 5-HT1A receptor agonist and selective serotonin reuptake inhibitor.
YU-238259
(Catalog# : 1710139, Cas# :
1943733-16-1
)
YU238259 exhibits potent synthetic lethality in the setting of DNA damage response an
Y-29794 Tosylate
(Catalog# : 1791521, Cas# :
143984-17-2
)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
Y15 hydrochloride
(Catalog# : 17030112, Cas# :
4506-66-5
)
Y15 hydrochloride, also known as FAK Inhibitor 14, is a direct FAK autophosphorylatio
Y-39983 HCl
(Catalog# : 17021305, Cas# :
173897-44-4
)
Y-39983 is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 o
740 Y-P (PDGFR 740Y-P)
(Catalog# : 17021302, Cas# :
1236188-16-1
)
740 Y-P is cell-permeable phosphopeptide activator ofPI3K. The PDGFR 740Y-P peptide s
YM-58483 (BTP2)
(Catalog# : 17109009, Cas# :
223499-30-7
)
YM-58483/BTP2 is a blocker of store-operated Ca2+ entry (SOCE), which regulates the a
YM-90709
(Catalog# : 16122849, Cas# :
163769-88-8
)
YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL
Y-29794 Tosylate
(Catalog# : 16122848, Cas# :
129184-48-1
)
Y-29794 Tosylate is an orally active, potent and specific non-peptide prolyl endopept
YHO-13351
(Catalog# : 6111512, Cas# :
1346753-00-1
)
YHO-13351 is the water-soluble prodrug of YHO-13177, which is a potent and specific i
YHO-13177
(Catalog# : 6111511, Cas# :
912287-56-0
)
YHO-13177 is a potent and specific inhibitor of BCRP; potentiated the cytotoxicity of
YM-155 hydrochloride
(Catalog# : 6111414, Cas# :
355406-09-6
)
YM155 is a potent survivin suppressant by inhibiting Survivin promoter activity with
YLF-466D
(Catalog# : 611813, Cas# :
1273323-67-3
)
YLF-466D is an allosteric AMPK activator.YLF466D activated recombinant human 111, 211
Y27632(free base)
(Catalog# : 16070918, Cas# :
146986-50-7
)
Y27632 is a selective ROCK inhibitor, which inhibits ET-1-induced increases in natriu
YK11
(Catalog# : 030910, Cas# :
1370003-76-1
)
Coming soon!
Y-27632 dihydrochloride
(Catalog# : 010421, Cas# :
129830-38-2
)
Y-27632 2Hcl is a selective ROCK1 (p160ROCK) inhibitor with Ki of 140 nM, exhibits &g
YM-201636
(Catalog# : 121426, Cas# :
371942-69-7
)
YM201636 is a selective PIKfyve inhibitor with IC50 of 33 nM, less potent to p110.
YL-109
(Catalog# : 110219, Cas# :
36341-25-0
)
YL-109 has ability to inhibit breast cancer cell growth and invasiveness in vitro and
Y-320
(Catalog# : 52516, Cas# :
288250-47-5
)
Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD
Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran