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MAPK
Membrane Transporter/Ion Channel
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index X
XRD-0394
(Catalog# : 25042, Cas# :
2595308-10-2
)
XRD-0394 is a DNA-PKcs inhibitor. XRD-0394 selectively targets, binds to and inhibits
XJTU-L453
(Catalog# : 24074, Cas# :
3008290-92-1
)
XJTU-L453 is a PI3Kα inhibitor with an IC50 value of 0.4 nM. XJTU-L453 can inhibit t
XPW1
(Catalog# : 20659, Cas# :
2700286-66-2
)
XPW1 is a potent and selective CDK9 inhibitor with excellent activity against clear c
XL092
(Catalog# : 20506, Cas# :
2367004-54-2
)
XL092 is an ATP-competitive inhibitor of multiple RTKs including MET, VEGFR2, AXL and
Xanomeline tartrate
(Catalog# : 2112067, Cas# :
152854-19-8 (tartrate)
)
Xanomeline (LY-246,708) is an orthosteric muscarinic acetylcholine receptor (mAChR) a
XP-59
(Catalog# : 2071549, Cas# :
890402-73-0
)
XP-59 is a potent inhibitor of the SARS-CoV Mpro
XP-23829
(Catalog# : 192143, Cas# :
1208229-58-6
)
XP-23829, also known as tepilamide fumarate, is a hydroxycarboxylic acid receptor 2 l
Ximelagatran
(Catalog# : 185282, Cas# :
192939-46-1
)
Ximelagatran is an anticoagulant that has been investigated extensively as a replacem
XMU-MP-1
(Catalog# : 18579, Cas# :
2061980-01-4
)
XMU-MP-1 is a potent and selective MST1/2 inhibitor.
XMD8-92
(Catalog# : 17030608, Cas# :
1234480-50-2
)
XMD8-92 is a BMK1 inhibitor and a highly selective inhibitor of ERK5 activity. XMD8-9
XMD16-5
(Catalog# : 17021312, Cas# :
1345098-78-3
)
XMD16-5 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 16 n
XMD8-87
(Catalog# : 17021311, Cas# :
1234480-46-6
)
XMD8-87 is a novel tyrosine kinase nonreceptor 2(TNK2) inhibitor with IC50s of 38 n
7-xylosyltaxol
(Catalog# : 611947, Cas# :
90332-66-4
)
7-xylosyltaxol(Taxol-7-xyloside) is a taxol (Paclitaxel) derivative; Paclitaxel binds
XL388
(Catalog# : 161009016, Cas# :
1251156-08-7
)
XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-B
XMD17-109
(Catalog# : 16071410, Cas# :
1435488-37-1
)
XMD17-109 is a novel, specific inhibitor of ERK-5 with an EC50 value of 4.2 M in HEK2
XCT790
(Catalog# : 16071016, Cas# :
725247-18-7
)
XCT790 is a potent and specific inverse agonist of ERR. XCT790 shows no significant a
XY1
(Catalog# : 021803, Cas# :
1624117-53-8
)
XY1 is a very close analogue of SGC707 (a potent, selective, and non-competitive inhi
X-396
(Catalog# : 011804, Cas# :
1365267-27-1
)
X-396 is an orally available small molecule inhibitor of the receptor tyrosine kinase
XL228
(Catalog# : 123011, Cas# :
898280-07-4
)
XL228 is a protein kinase inhibitor targeting IGF1R, the Aurora kinases, FGFR1-3, ABL
XEN907
(Catalog# : 112006, Cas# :
912656-34-9
)
XEN907 is a spirooxindole blocker of NaV1.7 for the treatment of pain.
XL765
(Catalog# : 111910, Cas# :
1123889-87-1
)
XL765 is a PI3K/mTOR dual kinase inhibitor with IC50 values of 157 nM, 39 nM, 113 nM,
XL647
(Catalog# : 111301, Cas# :
781613-23-8
)
XL647 is an orally bioavailable small-molecule receptor tyrosine kinase inhibitor wit
XL147
(Catalog# : 51506, Cas# :
956958-53-5
)
XL147 (SAR245408) is a potent and highly selective inhibitor of class I PI3Ks (, , ,
XAV-939
(Catalog# : 52632, Cas# :
284028-89-3
)
XAV939 is a small molecule and selective Wnt pathway -catenin-mediated transcription
XEN445
(Catalog# : 52501, Cas# :
1515856-92-4
)
XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME a
Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran