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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index I
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Name Index I
Irafamdastat (Synonyms: BMS-986368)
(Catalog# : 25154, Cas# :
2244136-58-9
)
Irafamdastat (BMS-986368; formerly known as ABX-1772) is an oral, CNS-penetrant, smal
Imlunestrant
(Catalog# : 25104, Cas# :
2408840-26-4
)
Imlunestrant is a biochemical
5-Iodo-4-methyl-1H-indole-2-carbonitrile
(Catalog# : 25096, Cas# :
3007670-38-1
)
Imarikiren
(Catalog# : 25093, Cas# :
1202265-63-1
)
Imarikiren, also known as TAK-272, is a potent, selective and orally active direct re
Imarikiren HCl
(Catalog# : 25092, Cas# :
1202269-24-6
)
Imarikiren, also known as TAK-272, is a potent, selective and orally active direct re
Irpagratinib
(Catalog# : 25089, Cas# :
2230974-62-4
)
Irpagratinib is an orally bioavailable, selective inhibitor of human fibroblast growt
Ivospemin Hydrochloride
(Catalog# : 25044, Cas# :
259657-09-5
)
Ivospemin is an antineoplastic spermine analogue.
Isolithocholic Acid
(Catalog# : 24146, Cas# :
1534-35-6
)
Isolithocholic acid is a bile acid that is formed via microbial metabolism of lithoch
Inupadenant
(Catalog# : 24138, Cas# :
2246607-08-7
)
Inupadenant, also known as EOS-850, is a highly selective small molecule antagonist o
Icovamenib
(Catalog# : 24097, Cas# :
2448172-22-1
)
This product was removed for commercial reasons.
Ifebemtinib
(Catalog# : 24092, Cas# :
1227948-82-4
)
Ifebemtinib, also known as BI-853520 and IN-10018, is a novel, highly selective PTK2
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Icosapent ethyl
(Catalog# : 24045, Cas# :
86227-47-6
)
Icosapent ethyl is used for the treatment of hypertriglyceridemia.
IMP-1088
(Catalog# : 24029, Cas# :
2059148-82-0
)
IMP-1088 is a potenthuman N-myristoyltransferases NMT1andNMT2dual inhibitor.
IK-930
(Catalog# : 20656, Cas# :
2563892-44-2
)
IK-930 is a novel, selective, small molecule inhibitor of TEAD that prevents palmitat
Iptacopan hydrochloride hydrate
(Catalog# : 20649, Cas# :
2447007-60-3
)
Iptacopan hydrochloride hydrate is a highly potent and highly selective factor B inhi
Itruvone
(Catalog# : 20623, Cas# :
21321-89-1
)
Itruvone is an antidepressant.
ITK inhibitor 6
(Catalog# : 20591, Cas# :
2404604-06-2
)
Imlunestrant
(Catalog# : 20475, Cas# :
2408840-26-4
)
Imlunestrant is a biochemical
1-ISOPROPOXYBENZENE
(Catalog# : 20406, Cas# :
2741-16-4
)
IACS-13909
(Catalog# : 822221, Cas# :
2160546-07-4
)
IACS-13909 is a specific and potent allosteric inhibitor of SHP2, that suppresses sig
IMM-H007
(Catalog# : L20336, Cas# :
1221412-23-2
)
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
Indirubin-3’-oxime
(Catalog# : L20330, Cas# :
160807-49-8
)
Indirubin-3’-oxime is a potent inhibitor of glycogen synthase kinase 3β (GSK3β; I
Ispronicline
(Catalog# : 20288, Cas# :
252870-53-4(free base)
)
Ispronicline, also known as AZD3480; TC 1734; TC-0173, and RJR 1734, is a alpha4beta2
indole-4-boronic acid pinacol ester
(Catalog# : 21253, Cas# :
388116-27-6
)
indole-4-boronic acid pinacol ester, CAS 388116-27-6, is an important intermeidate.
IOX4
(Catalog# : 20122401, Cas# :
1154097-71-8
)
9-ING-41
(Catalog# : 2091905, Cas# :
1034895-42-5
)
9-ING-41 is a glycogen synthase kinase-3 (GSK-3) inhibitor.
IACS-9439
(Catalog# : 20911, Cas# :
2231259-57-5
)
IACS-9439 is a potent, highly selective and orally bioavailable CSF1R inhibitor. IACS
IITZ-01
(Catalog# : 2071519, Cas# :
1807988-47-1
)
IITZ-01 (Autophagy inhibitor IITZ-01) is a novel potent lysosomotropic autophagy inhi
4-iodo-2-isopropyl-1-Methyl-1H-iMidazole
(Catalog# : 2062023, Cas# :
851870-24-1
)
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MTX115325
(Catalog# : 186264, Cas# :
2750895-97-5
)
MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with good drug-like
LY-3381916
(Catalog# : 193123, Cas# :
2166616-75-5
)
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, bi
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
CAY 10566
(Catalog# : 10403, Cas# :
944808-88-2
)
CAY 10566 is a potent selective SCD-1 inhibitor.
Cadefrecitinib (GLPG-3667)
(Catalog# : 20509, Cas# :
2308520-97-8
)
Cadefrecitinib (GLPG-3667) is an oral, small molecule inhibitor of the TYK2 kinase in
QBS10072S
(Catalog# : 25190, Cas# :
1802735-28-9
)
QBS10072S isa blood-brain-barrier (BBB) penetrative agent composed of a cytotoxic che
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes