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Inhibitors & Agonists

CATALOG NOPRODUCT NAMECASPURITYSTRUCTURE
102703AZD-88351620576-64-8≧98.0%
AZD8835 is a potent and selective inhibitor of PI3Kalpha and PI3Kdelata with excellen
16071024Emricasan254750-02-298%
Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspaseinhibitor with
711401IPI-549(IPI549)1693758-51-898% 
IPI-549 is a potent and selective phosphoinositide-3-kinase (PI3K) Inhibitor as an Im
51701PF-064639221454846-35-598% 
PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosin
51908Baricitinib1187594-09-798% 
Baricitinib (also known as LY3009104 or INCB028050) is a novel and potent small molec
51605LY2835219(Abemaciclib)1231930-82-798% 
LY2835219 is a potent and selective inhibitor ofCDK4andCDK6withIC50of 2 nM and 10 nM,
51907Alectinib(CH5424802)1256580-46-798.5%
Alectinibis a second-generation, orally active, potent and highly selective inhibitor
52020Golvatinib (E7050)928037-13-298% 
Golvatinib (E7050) is a dualc-MetandVEGFR-2inhibitor with IC50 of 14 nM and 16 nM, do
51912KRN 633286370-15-898% 
KRN 633 is an ATP-competitive inhibitor ofVEGFR1/2/3withIC50of 170 nM/160 nM/125 nM,
51609R788 (Fostamatinib) Disodium1025687-58-498% 
R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is aSykinhibit
51803Semaxanib (SU5416)204005-46-998% 
Semaxanib (SU5416) is a potent and selectiveVEGFR(Flk-1/KDR) inhibitor withIC50of 1.2
52006TGX-221663619-89-498% 
TGX-221 is ap110-specific inhibitor withIC50of 5 nM, 1000-fold more selective for p11