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MAPK
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index S
SOP1812 (QN-302)
(Catalog# : 20639, Cas# :
2546091-70-5
)
QN-302 is a G-quadruplex (G4)-selective transcription inhibitor.
SEW2871
(Catalog# : 20604, Cas# :
256414-75-2
)
SEW2871 is a S1P1 agonist (sphingosine-1-phosphate type 1 receptor agonist). SEW2871
STX-721
(Catalog# : 20576, Cas# :
2765525-82-2
)
STX-721 is a next-generation, orally delivered therapy, designed with potential best-
STC-15
(Catalog# : 20549, Cas# :
2648257-56-9
)
STC-15 is a first-in-class inhibitor of RNA modification and is the first ever RNA me
(S)-1-BOC-2-METHYL-[1,4]DIAZEPANE
(Catalog# : 20541, Cas# :
194032-32-1
)
(S)-5-fluoro-3-methylbenzo[c][1,2]oxaborol-1(3H)-ol
(Catalog# : 20522, Cas# :
2921961-53-5
)
(S)-3-AMINO-3-(4-CHLORO-PHENYL)-PROPIONIC ACID
(Catalog# : 20516, Cas# :
131690-60-3
)
Samidorphan
(Catalog# : 20454, Cas# :
852626-89-2
)
Samidorphan, also known as ALKS-33 and RDC-0313, is an opioid modulator with μ-antag
Spiro[cyclohexane-1,9'(6'H)-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidine]-7'(8'H)-carboxylic acid, 2'-(methylthio)-6'-oxo-5'-[[(trifluoromethyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester
(Catalog# : 20412, Cas# :
2170746-98-0
)
(S)-1-(6-(4-fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethanamine
(Catalog# : 20396, Cas# :
1980023-96-8
)
SB-4 agonist
(Catalog# : G20378, Cas# :
100874-08-6
)
SB 4 is a potent BMP4 agonist.
SEP-363856 HCl ( SEP-856 )
(Catalog# : 822222, Cas# :
1310422-41-3 (HCl)
)
SEP-363856 is a novel trace amine receptor 1 (TAAR1) agonist with serotonin 5-HT1A ac
SRI-37330 free base
(Catalog# : 1711224, Cas# :
2322245-42-9 (free base)
)
SRI-37330 is a novel inhibitor of TXNIP expression, decreasing glucagon secretion and
Sunvozertinib ( DZD 9008 )
(Catalog# : 20369, Cas# :
2370013-12-8
)
Sunvozertinib, also known as DZD9008, is an oral, potent, irreversible, and selective
SHMT-IN-2
(Catalog# : 20368, Cas# :
2102681-49-0
)
SHMT-IN-2 is a serine hydroxymethyltransferase (SHMT) inhibitor, potently inhibiting
SRI-011381
(Catalog# : L20355, Cas# :
1629138-41-5
)
SRI-011381 is an agonist of the TGF-beta signaling pathway for treatment of Alzheimer
SJ-172550
(Catalog# : L20353, Cas# :
431979-47-4
)
SJ-172550, also known as MDMX Inhibitor II, is an inhibitor of MDMX that disrupts MDM
SMN-C3
(Catalog# : 20344, Cas# :
1449597-34-5
)
SMN-C3is an orally active SMN2 splicing modulator and has the potential to treat spin
Stafia-1
(Catalog# : L20338, Cas# :
2582757-90-0
)
STM2457
(Catalog# : 20321, Cas# :
2499663-01-1
)
STM2457 is a highly potent and selective first-in-class catalytic inhibitor of METTL3
SRI-37330 HCl
(Catalog# : 20306, Cas# :
2322245-49-6
)
SRI-37330 hydrochloride is a novel inhibitor of TXNIP expression,and dose-dependently
SM-102
(Catalog# : 21252, Cas# :
2089251-47-6
)
SM-102 is an ionizable amino lipid that has been used in combination with other lipid
Seralutinib
(Catalog# : 21238, Cas# :
1619931-27-9
)
Seralutinib, also known as PK-10571 and GB002, is a Novel Inhaled Pdgfr Kinase Inhibi
Sonidegib (LDE-225)
(Catalog# : 21232, Cas# :
956697-53-3
)
Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable
SB-366791
(Catalog# : 21230, Cas# :
472981-92-3
)
SB-366791 is a potent and selective TRPV1 antagonist. SB-366791 inhibits glutamatergi
Scriptaid
(Catalog# : 21229, Cas# :
287383-59-9
)
Scriptaid, also known as GCK 1026, is a HDAC inhibitor. Scriptaid protects against tr
SNG-1153
(Catalog# : 21228, Cas# :
1446712-19-1
)
SNG-1153 is a modulator of estrogen receptor ER-alpha36.
Seltorexant
(Catalog# : 81498, Cas# :
1293281-49-8
)
Seltorexant, also known as JNJ-42847922 and MIN-202, is a selective orexin-2 receptor
Samelisant
(Catalog# : 20123101, Cas# :
1415792-84-5
)
Samelisant is a novel, highly selective and potent small molecule oral inhibitor targ
Senaparib
(Catalog# : 20103002, Cas# :
1401682-78-7
)
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes
CBR-470-1
(Catalog# : 25192, Cas# :
2416095-06-0
)
CBR-470-1 is an Inhibitor of the glycolytic enzyme PGK1that induces Nrf2 activity.
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
Flavopiridol ( Alvocidib )
(Catalog# : 237071, Cas# :
146426-40-6
)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
AG-270
(Catalog# : 25176, Cas# :
2201056-66-6
)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa