MRT-6160 (DDY391) is a potent, highly selective, and orally bioavailable investigational molecular glue degrader of VAV1, which in vitro studies has shown deep degradation of its target with no detectable effects on other proteins.
For research use only. We do not sell to patients.
| Name | MRT-8102 |
|---|---|
| Iupac Chemical Name | N-(3,5-dichloro-4-(2,6-dioxopiperidin-3-yl)benzyl)-2-methyl-2-(5-methylpyrimidin-2-yl)propanamide |
| Synonyms | MRT-8102; MRT8102; MRT 8102 |
| Molecular Formula | C21H22Cl2N4O3 |
| Molecular Weight | 449.33 |
| Smile | O=C1NC(C(C2=C(Cl)C=C(C=C2Cl)CNC(C(C)(C3=NC=C(C=N3)C)C)=O)CC1)=O |
| InChiKey | VKROEWYACWPSOG-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H22Cl2N4O3/c1-11-8-24-19(25-9-11)21(2,3)20(30)26-10-12-6-14(22)17(15(23)7-12)13-4-5-16(28)27-18(13)29/h6-9,13H,4-5,10H2,1-3H3,(H,26,30)(H,27,28,29) |
| CAS Number | 3069891-91-1 |
| Related CAS | 3069891-91-1 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |