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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index M
MAT2A-IN-23
(Catalog# : 25210, Cas# :
2925324-58-7
)
MAT2A-IN-23 39 is a potent MTA2A inhibitor.
MK256
(Catalog# : 25208, Cas# :
2271348-04-8
)
MK256 is a novel CDK8 inhibitor with potent antitumor activity in AML through downreg
MA242 TFA
(Catalog# : 25206, Cas# :
1049704-18-8
)
MA242 isMDM2 and NFAT1 dual inhibitorthat induces MDM2 auto-ubiquitination and degrad
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
MTX115325
(Catalog# : 186264, Cas# :
2750895-97-5
)
MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with good drug-like
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)
MSC2360844 hemifumarate
(Catalog# : 25130, Cas# :
1621688-31-0
)
Maralixibat Chloride
(Catalog# : 25126, Cas# :
228113-66-4
)
Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid trans
4-Methyl-1H-indole-2-carbonitrile
(Catalog# : 25097, Cas# :
1541530-91-9
)
Miricorilant
(Catalog# : 25090, Cas# :
1400902-13-7
)
Miricorilant is discontinued.
MGD-28
(Catalog# : 25073, Cas# :
2991818-13-2
)
MGD-28 is a potent molecular glue degrader that demonstrates significant in vitro eff
MFI8
(Catalog# : 25057, Cas# :
694488-83-0
)
MFI8 is a Mitochondrial Fusion Inhibitor
MS6105
(Catalog# : 25039, Cas# :
2891709-58-1
)
M3554
(Catalog# : 25017, Cas# :
2763252-25-9
)
M3554, a novel anti-GD2 antibody drug conjugate.
MD-43
(Catalog# : 25016)
MD-43 is a potent and selective degrader of MCT4.
ML-202
(Catalog# : 24158, Cas# :
1221186-52-2
)
ML-202 is an activator of pyruvate kinase M2 (PKM2).
ML353
(Catalog# : 24151, Cas# :
2990506-75-5
)
ML353 is a selective ligand of mGlu5 silent allosteric modulator (SAM).
MIF098
(Catalog# : 24150, Cas# :
1208448-95-6
)
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.
Mevrometostatum
(Catalog# : 24124, Cas# :
1844849-10-0
)
Mevrometostatum is an enhancer of zeste homolog 2 (EZH2) inhibitor.
3-(methylsulfonyl)propanenitrile
(Catalog# : 24044, Cas# :
54863-37-5
)
Dapansutrile is a potent, orally active and selectiveNLRP3inflammasome inhibitor. Dap
Mavoglurant
(Catalog# : 20675, Cas# :
543906-09-8
)
MRTX1719
(Catalog# : 262401, Cas# :
2630904-45-7
)
MRTX1719 is a potent and selective binder to the PRMT5•MTA complex and selectively
Mavodelpar
(Catalog# : 20615, Cas# :
942594-93-6
)
Mavodelpar is a peroxisome proliferator activated receptor (PPAR) delta agonist.
MRTX849
(Catalog# : 20611, Cas# :
2326521-71-3
)
Adagrasib, also known as MRTX849, is a potent, highly selective, oral available KRAS
Migoprotafib
(Catalog# : 20592, Cas# :
2377352-49-1
)
Migoprotafib, also known as GDC-1971 and RLY-1971, is a SHP2 allosteric inhibitor. GD
Mtb-IN-2
(Catalog# : 20572, Cas# :
2861190-30-7
)
Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis
MBX-8025 lysine anhydrous
(Catalog# : 20542, Cas# :
928821-41-4
)
MBX-8025 lysine anhydrous is a selective PPAR-delta agonist.
Milademetan free base
(Catalog# : 20529, Cas# :
1398568-47-2
)
Milademetan, also known as DS-3032b or DS-3032, is a potent and selective MDM2 inhibi
muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)
LLL12
(Catalog# : 25075, Cas# :
1260247-42-4
)
LLL12 is a potent STAT3 inhibitor.
ECC-5004
(Catalog# : 26A015, Cas# :
2758659-09-3
)
ECC5004 (AZD5004) is a novel small-molecule GLP-1 RA for use as an oral therapy for c
SILA-123
(Catalog# : 26A014, Cas# :
2911585-37-8
)
SILA-123 is a type II FLT3 inhibitor that has shown highly potent inhibitory effects
Encaleret sulfate
(Catalog# : 26A013, Cas# :
1214922-52-7
)
Encaleret is an investigational small molecule antagonist of the calcium sensing rece
Iadademstat ( ORY-1001 ) hydrochloride
(Catalog# : 26A011, Cas# :
1431303-72-8
)
Iadademstat (ORY-1001) is an orally active, highly potent and selective inhibitor of
DPTX-3186
(Catalog# : 26A010)
DPTX3186, an orally administered small molecule condensate modulator (c-mod) inhibiti
Velzatinib (IDRX-42, M-4205)
(Catalog# : 26A009, Cas# :
2590556-80-0
)
Velzatinib is an orally bioavailable small molecule inhibitor of multiple mutated for
Soficitinib
(Catalog# : 26A008, Cas# :
2574524-67-5
)
Soficitinibis a small-molecule inhibitor of non-receptor tyrosine-protein kinase (TYK
Ofirnoflast
(Catalog# : 26A007, Cas# :
2731294-23-6
)
Ofirnoflast is a first-in-class, orally bioavailable NEK7 inhibitor.