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4SC-202

Catalog No.: 161227110
Cas No.: 910462-43-0
Purity : 98% 
161227110 - 4SC-202 | CAS 910462-43-0

Catalog number : 161227110

CAS number : 910462-43-0

Molecular Formula : C23H21N5O3S 

Molecular Weight : 447.51 

Iupac Chemical Name : 4SC-202 

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SynonymsN/A 
Molecular FormulaC23H21N5O3S 
Molecular Weight447.51 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone deacetylases (HDACs) isoenzymes 1, 2 and 3, with potential antineoplastic activity. HDAC inhibitor 4SC-202 selectively binds to and inhibits class I HDACs leading to an accumulation of highly acetylated histones. This may result in an induction of chromatin remodeling, the selective transcription of tumor suppressor genes, and the tumor suppressor protein-mediated inhibition of tumor cell division and eventually the induction of tumor cell apoptosis. This may inhibit tumor cell proliferation in susceptible tumor cells. HDACs, upregulated in many tumor types, are a class of enzymes that deacetylate chromatin histone proteins. 

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