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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
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Name Index P
PF-04979064
(Catalog# : 611902, Cas# :
1220699-06-8
)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
PQR620
(Catalog# : 611821, Cas# :
1927857-56-4
)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
PP121
(Catalog# : 161009011, Cas# :
1092788-83-4
)
PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyros
PF-4989216
(Catalog# : 161009002, Cas# :
1276553-09-3
)
PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently
PIK-294
(Catalog# : 160926013, Cas# :
900185-02-6
)
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110
PIK-90
(Catalog# : 160926010, Cas# :
677338-12-4
)
PIK-90 is a potent PI3K inhibitor with potential anticancer activity.
PIK-93
(Catalog# : 160926009, Cas# :
593960-11-3
)
PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinas
PI-103
(Catalog# : 160926002, Cas# :
371935-74-9
)
It inhibits ATR and ATM only at much higher concentrations (IC50= 850 and 920 nM, res
PNU-159682
(Catalog# : 16071409, Cas# :
202350-68-3
)
PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsom
Pevonedistat
(Catalog# : 16071408, Cas# :
905579-51-3
)
Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Ne
PRX-08066
(Catalog# : 16071114, Cas# :
866206-54-4
)
PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotal
PS 48
(Catalog# : 16071111, Cas# :
1180676-32-7
)
PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1,
Panulisib
(Catalog# : 16071030, Cas# :
1356033-60-7
)
Panulisib, also known as AK151761, is a potent and selective imidazoquinoline based P
Piclidenoson
(Catalog# : 16071028, Cas# :
152918-18-8
)
Piclidenoson, also known as CF101, is a specific agonist to the A3 adenosine receptor
Pirarubicin
(Catalog# : 16070806, Cas# :
72496-41-4
)
Pirarubicin is an anthracycline drug. An analogue of the anthracycline antineoplastic
PS47
(Catalog# : 16070703, Cas# :
1180676-33-8
)
PS47
PIK-293
(Catalog# : 16062804, Cas# :
900185-01-5
)
PIK-293 is a PI3K inhibitor
5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione
(Catalog# : 16062108, Cas# :
1477-24-3
)
5-PYRIDIN-4-YL-4H-[1,2,4]TRIAZOLE-3-THIOL
Paritaprevir
(Catalog# : 16060702, Cas# :
1216941-48-8
)
Paritaprevir, also known as ABT-450, is an acylsulfonamide inhibitor of the NS3-4A se
PXD-101
(Catalog# : 16053002, Cas# :
866323-14-0
)
Belinostat (trade name Beleodaq, previously known as PXD101) is a histone deacetylase
PS-1145
(Catalog# : 032501, Cas# :
431898-65-6
)
Coming soon!
2-Pyridinemethanamine, N-[2-(diphenylphosphino)ethyl]-
(Catalog# : 032407, Cas# :
1388712-98-8
)
Coming soon!
PF-06424439
(Catalog# : 020202, Cas# :
1469284-78-3
)
PF-06424439 is a potent and selective Diacylglycerol Acyltransferase 2 ( DGAT2) inhib
PF-06471553
(Catalog# : 020201, Cas# :
1808094-07-6
)
PF-06471553 is a potent and selective Monoacylglycerol acyltransferase 3 (MGAT3) inhi
PF-06282999
(Catalog# : 020102, Cas# :
1435467-37-0
)
PF-06282999 is an irreversible inactivator of myeloperoxidase, and currently in clini
PF-3274167
(Catalog# : 020101, Cas# :
900510-03-4
)
PF-3274167 is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki
Pifithrin-alpha
(Catalog# : 012011, Cas# :
63208-82-2
)
Pifithrin- is an inhibitor of p53, inhibiting p53-dependent transactivation of p53-re
PF-04880594
(Catalog# : 012008, Cas# :
1111636-35-1
)
PF-04880594 is a RAF inhibitor, which induces ERK phosphorylation and RAF dimerizatio
PF-2545920
(Catalog# : 012006, Cas# :
898562-94-2
)
PF-2545920 is a phosphodiesterase inhibitor selective for the PDE10A subtype, which i
Pyriofenone
(Catalog# : 011119, Cas# :
688046-61-9
)
Coming soon!
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
N-Methylamisulpride ( Synonyms: LB-102 )
(Catalog# : 26A058, Cas# :
2227154-23-4
)
N-Methylamisulpride (Synonyms: LB-102) is a dopamine D2 and D3 receptor antagonist an
Safusidenib Erbumine
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Repinatrabit ( Synonyms: JNT-517 )
(Catalog# : 26A056, Cas# :
2837993-05-0
)
Repinatrabit (JNT-517) is an investigational, selective, small-molecule inhibitor of
Privosegtor ( Synonyms: OCS-05, ACT-01 )
(Catalog# : 26A055, Cas# :
1361200-34-1
)
Privosegtor (OCS-05, ACT-01) is a small molecule peptidomimetic, BDNF/NT-3 growth fac
ART-6043
(Catalog# : 26A054, Cas# :
2923356-52-7
)
ART-6043 is an oral, small-molecule inhibitor of the DNA polymerase theta (POLQ).
Palacaparib ( Synonyms: AZD-9574 )
(Catalog# : 26A053, Cas# :
2756333-39-6
)
Palacaparib (AZD-9574) is an orally available, CNS penetrant, PARP-1 inhibitor.
IPG-7236
(Catalog# : 26A052, Cas# :
2756350-91-9
)
IPG-7236 is a C-C chemokine receptor type 8 (CCR8) antagonist.
Mocaciclib ( Synonyms: Q-901 )
(Catalog# : 26A051, Cas# :
2766124-39-2
)
Mocaciclib (Q-901) is a cyclin-dependent kinase-7 (CDK-7) inhibitor.
Eratrectinib ( Synonyms: VC-004 )
(Catalog# : 26A050, Cas# :
2396516-98-4
)
Eratrectinib (VC-004) is a small molecule inhibitor of the nerve growth factor recept
SCY-770 ( Synonyms: PXL-770 )
(Catalog# : 26A049, Cas# :
1523493-78-8
)
SCY-770 (PXL-770) is a direct adenosine monophosphate-activated protein kinase (AMPK)