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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index P
PKC412
(Catalog# : 123013, Cas# :
120685-11-2
)
PKC412 is a broad spectrum protein kinase inhibitor; inhibits conventional PKC isofor
Plerixafor octahydrochloride
(Catalog# : 123004, Cas# :
155148-31-5
)
Plerixafor octahydrochloride is a chemokine receptor antagonist for CXCR4 and CXCL12-
PF-3084014
(Catalog# : 122950, Cas# :
1290543-63-3
)
PF-3084014 is a novel -secretase inhibitor that reduces amyloid-beta (Abeta) producti
Pacritinib ( SB1518 )
(Catalog# : 122941, Cas# :
937272-79-2
)
Pacritinib(SB1518) is a highly selective kinaseinhibitorwith specificity for JAK2, FL
PHA-848125
(Catalog# : 122916, Cas# :
802539-81-7
)
PHA-848125 is a potent, ATP-competitive CDK inhibitor for CDK2 with IC50 of 45 nM; &g
PI-3065
(Catalog# : 122908, Cas# :
955977-50-1
)
PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhib
PD 123319
(Catalog# : 122903, Cas# :
130663-39-7
)
PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of
PNU-282987
(Catalog# : 122827, Cas# :
123464-89-1
)
PNU-282987 is a selective 7 nicotinic acetylcholine receptor(7 nAChR) agonist with Ki
PF-431396
(Catalog# : 122818, Cas# :
717906-29-1
)
PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK
Posaconazole
(Catalog# : 122815, Cas# :
171228-49-2
)
Posaconazole is a broad-spectrum, second generation, triazole compound with antifunga
PQ401
(Catalog# : 122806, Cas# :
196868-63-0
)
PQ401, a selective insulin-like growth factor-1 receptor blocker, is a novel diarylur
Pardoprunox
(Catalog# : 122523, Cas# :
269718-84-5
)
Pardoprunox is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT
PKC-IN-1
(Catalog# : 122520, Cas# :
1046787-18-1
)
PKC-IN-1 is a poent PKC beta II inhibitor with Ki of 14.9 nM; compound example H6 fro
PF-04447943
(Catalog# : 122515, Cas# :
1082744-20-4
)
PF-04447943 is a potent, selective brain penetrant PDE9 inhibitor (Ki of 2.8, 4.5 and
PD-0325901
(Catalog# : 122405, Cas# :
391210-10-9
)
PD-0325901 i a potent bioavailable and selective MEK inhibitor, which targets mitogen
P005672 hydrochloride
(Catalog# : 122302, Cas# :
1035979-44-2
)
P005672 hydrochloride is used for antibacterial/anti-inflammatory acne treatment.
Pirodavir
(Catalog# : 122216, Cas# :
124436-59-5
)
Pirodavir is the prototype of a novel class of broad-spectrum antipicornavirus compou
PD173074
(Catalog# : 122212, Cas# :
219580-11-7
)
PD173074 is a small-molecule FGFR3-selective tyrosine kinase inhibitor (TKI), as a th
Pyroxamide
(Catalog# : 121802, Cas# :
382180-17-8
)
Pyroxamide is a synthetic derivative of hydroxamic acid with antineoplastic propertie
PKI-402
(Catalog# : 121421, Cas# :
1173204-81-3
)
PKI-402 is a potent dual pan-PI3K/mTOR inhibitor targeting PI3K/// and mTOR with IC50
PHA-665752
(Catalog# : 121418, Cas# :
477575-56-7
)
PHA-665752 is a potent, selective and ATP-competitive c-Met inhibitor with IC50 of 9
Pimavanserin
(Catalog# : 120809, Cas# :
706779-91-1
)
Pimavanserin is an inverse agonist on the serotonin receptor subtype 5-HT2A, with 40x
Pemetrexed disodium
(Catalog# : 120704, Cas# :
150399-23-8
)
Coming soon!
PX-478
(Catalog# : 111307, Cas# :
685847-78-3
)
PX-478 is HIF-1alpha inhibitor, is also an orally active small molecule with potentia
Pardoprunox hydrochloride
(Catalog# : 111010, Cas# :
269718-83-4
)
Pardoprunox hydrochloride is a novel partial dopamine D2 and D3 receptor agonist and
PD153035 Hcl
(Catalog# : 111003, Cas# :
183322-45-4
)
PD153035 Hcl is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM an
PRT-060318
(Catalog# : 110904, Cas# :
1194961-19-7
)
PRT-060318 is a novel selective inhibitor of the tyrosine kinase Syk, as an approach
PCI-27483
(Catalog# : 110401, Cas# :
871266-63-6
)
PCI-27483 is a reversible small-molecule inhibitor of activated factor VII (factor VI
PSEUDOLARIC ACID B
(Catalog# : 110223, Cas# :
82508-31-4
)
Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempfer
PL-100
(Catalog# : 102616, Cas# :
612547-11-2
)
PL-100 is a novel HIV-1 protease inhibitor (PI) with a favorable cross-resistance pro
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi