PIK-294
Catalog No: 160926013
CAS Number: 900185-02-6
Purity: 98% by HPLC
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K//, respectively. PIK-294 has been used to help distinguish the unique roles of the various PI3-K isoforms. PIK-294 inhibited both chemokinetic and chemotactic CXCL8-induced migration.
For research use only. We do not sell to patients.
Chemical Information
| Name | PIK-294 |
|---|---|
| Iupac Chemical Name | 2-((4-amino-3-(3-hydroxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-5-methyl-3-(o-tolyl)quinazolin-4(3H)-one |
| Synonyms | PIK294; PIK 294; PIK-294. |
| Molecular Formula | C28H23N7O2 |
| Molecular Weight | 489.52792 |
| Smile | NC1=C2C(=NC=N1)N(N=C2C2=CC(=CC=C2)O)CC2=NC1=CC=CC(=C1C(N2C2=C(C=CC=C2)C)=O)C |
| InChiKey | WFSLJOPRIJSOJR-UHFFFAOYSA-N |
| InChi | InChI=1S/C28H23N7O2/c1-16-7-3-4-12-21(16)35-22(32-20-11-5-8-17(2)23(20)28(35)37)14-34-27-24(26(29)30-15-31-27)25(33-34)18-9-6-10-19(36)13-18/h3-13,15,36H,14H2,1-2H3,(H2,29,30,31) |
| CAS Number | 900185-02-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
