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MAPK
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index P
PP2
(Catalog# : 185146, Cas# :
172889-27-9
)
PP2, also known as AG 1879, is a substance that has frequently been used in cancer re
PP1
(Catalog# : 185145, Cas# :
172889-26-8
)
PP1 is a potent and selective Src family protein tyrosine kinase inhibitor.
Pocapavir
(Catalog# : 185144, Cas# :
146949-21-5
)
Pocapavir, also known as SCH-48973 and V-073, is a potent, selective, antienterovirus
PSMA617 TFA
(Catalog# : 185143, Cas# :
1702967-37-0
)
PSMA-617 is a ligand used to make 177Lu-PSMA-617, which is a radioactive molecule to
Pyridostatin TFA salt
(Catalog# : 185142, Cas# :
1472611-44-1
)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
PF-06260933
(Catalog# : 18544, Cas# :
1811510-56-1
)
PF-06260933 is a potent and highly selective inhibitor of MAP4K4.
PHA-767491 HCl
(Catalog# : 184286, Cas# :
942425-68-5
)
PHA-767491, also known as CAY10572, is a potent, ATP-competitive dual cdc7/cdk9 inhib
PLX51107
(Catalog# : 184285, Cas# :
1627929-55-8
)
PLX51107 is a potent and selective BRD4 inhibitor or BET inhibitor with novel in vitr
PD 158780
(Catalog# : 184284, Cas# :
171179-06-9
)
PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epide
PZM21
(Catalog# : 184162, Cas# :
1997387-43-5
)
PZM21 is a potent Gi activator with exceptional selectivity for μOR and minimal β-a
PF-9366
(Catalog# : 184107, Cas# :
72882-78-1
)
PF-9366 is a novel inhibitor of human methionine adenosyltransferase 2A (Mat2A), the
PFI-2 hydrochloride
(Catalog# : 184106, Cas# :
1627607-87-7
)
PFI-2 is a potent inhibitor of SETD7 with IC50 2 nM and 1000-fold selectivity over ot
PCI-29732
(Catalog# : 184101, Cas# :
330786-25-9
)
PCI-29732 is a BTK inhibitor. It acts by blocking B cell antigen receptor (BCR)-media
PF-0684000
(Catalog# : 184318, Cas# :
198474-05-4
)
PF-0684000, also known as EOS200271, is potent IDO-1 inhibitor (IC50 0.15 μM). PF-06
PF-06409577
(Catalog# : 18434, Cas# :
1467057-23-3
)
PF-06409577 is a potent and selective activator of 5′ adenosine monophosphate-activ
PRN-1371
(Catalog# : 17101614, Cas# :
1802929-43-6
)
PRN-1371 is a covalent, irreversible, highly selective FGFR1, 2, 3 and 4 inhibitor. P
PF-5006739
(Catalog# : 17101612, Cas# :
1293395-67-1
)
PF-5006739 is a Potent CK1δ/ε inhibitor. PF-5006739 attenuates opioid drug-seeking
PF-04628935
(Catalog# : 17101611, Cas# :
1383719-97-8
)
PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth ho
PIM447
(Catalog# : 1710134, Cas# :
1210608-43-7
)
PIM447, also known as LGH447, is a potent Moloney murine leukemia (PIM) 1, 2, and 3 k
PF-562271 HCl
(Catalog# : 179302, Cas# :
939791-41-0
)
PF-562271, also known as PF-562,271 and PF-271, is an orally bioavailable small molec
Pemafibrate
(Catalog# : 179221, Cas# :
848259-27-8
)
(1)Pemafibrate, also known as K-877 and (R)-K 13675, is a PPAR alpha agonist. (R)-K-1
Pyridostatin TFA salt
(Catalog# : 1791517, Cas# :
179474-81-8
)
Pyridostatin stabilizes G-quadruplexes (G4s) in cells and elicits a DNA damage respon
Prucalopride Succinate
(Catalog# : 1791516, Cas# :
179474-85-2
)
Prucalopride, also known as R-108512, is a selective, high affinity serotonin (5-HT4)
PRT4165
(Catalog# : 1791515, Cas# :
31083-55-3
)
PRT4165 is a small molecule inhibitor of polycomb repressive complex 1, which inhibit
Pramipexole HCl
(Catalog# : 1791510, Cas# :
104632-25-9
)
Pramipexole Dihydrochloride is an agonist of the Gαi-linked dopamine receptors D2, D
PF-06281355
(Catalog# : 1791312, Cas# :
1435467-38-1
)
PF-06281355, also known as PF-1355, is an orally available, selective and potent mech
Puromycin Aminonucleoside
(Catalog# : 1791310, Cas# :
58-60-6
)
Puromycin Aminonucleoside, also known as PAN, NSC3056, is useful in the study of huma
P7C3-OMe
(Catalog# : 179116, Cas# :
1235481-43-2
)
P7C3-OMe, also known as (R)-P7C3-OMe, is an analogue of P7C3 and P3C3-A20. P7C3 Atten
PF-CBP1 free base
(Catalog# : 179113, Cas# :
1962928-21-7
)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
PF-CBP1 HCl
(Catalog# : 179112, Cas# :
2070014-93-4
)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi