Welcome to Sun-shine chemical
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors & Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
Search
Home
Sitemaps
Name Index P
Search By Initial
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
1
2
3
4
5
6
7
8
9
«
4
5
6
7
8
9
10
»
Name Index P
PSI-7977
(Catalog# : 52718, Cas# :
1190307-88-0
)
PSI-7977(sofosbuvir) is an investigational nucleotide analog for treatment of chronic
Poziotinib
(Catalog# : 52634, Cas# :
1092364-38-9
)
Poziotinib(NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3
PF-4708671
(Catalog# : 52631, Cas# :
1255517-76-0
)
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), w
Perifosine
(Catalog# : 52613, Cas# :
157716-52-4
)
Perifosine (KRX-0401; D-21266; NSC 639966) is a novel Akt inhibitor with IC50 of 4.7
Plinabulin
(Catalog# : 52603, Cas# :
714272-27-2
)
Plinabulin (NPI-2358) is a vascular disrupting agents (VDA) against tubulin-depolymer
PLX-4720
(Catalog# : 52592, Cas# :
918505-84-7
)
PLX 4720 is a potent and selective inhibitor of B-RafV600E(IC50=13 nM) and c-Raf-1Y34
Palomid 529
(Catalog# : 52591, Cas# :
914913-88-5
)
Palomid 529 (P529) is a novel potent inhibitor of both the mTORC1 and mTORC2 complexe
PHT-427
(Catalog# : 52583, Cas# :
1191951-57-1
)
PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains o
Purvalanol A
(Catalog# : 52564, Cas# :
212844-53-6
)
Purvalanol A(NG-60) is a potent, cell-permeable, and selective inhibitor of cyclin-de
PI3K-IN-1
(Catalog# : 52560, Cas# :
1349796-36-6
)
PI3K-IN-1 is a potent inhibitor of PI3K, more information can be found in patent WO20
Purvalanol B
(Catalog# : 52559, Cas# :
212844-54-7
)
Purvalanol B(NG-95) is a cyclin-dependent kinase inhibitor with IC50 values of 6, 6,
Pracinostat
(Catalog# : 52552, Cas# :
929016-96-6
)
Pracinostat(SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with excepti
Purmorphamine
(Catalog# : 52519, Cas# :
483367-10-8
)
Purmorphamine, which directly binds and activates Smoothened, blocks BODIPY-cyclopami
PD 169316
(Catalog# : 52513, Cas# :
152121-53-4
)
PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor (IC50 =
PD153035
(Catalog# : 52223, Cas# :
153436-54-5
)
PD153035(ZM 252868; AG 1517) is a potent and specific inhibitor of EGFR with Ki and I
PPQ-102
(Catalog# : 52233, Cas# :
931706-15-9
)
PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride curre
PTC124c
(Catalog# : 52231, Cas# :
775304-57-9
)
PTC124 (Ataluren) selectively induces ribosomal read-through of premature but not nor
PR-619
(Catalog# : 52227, Cas# :
2645-32-1
)
PR-619 is a broad-range DUB inhibitor with potential for further development as a che
PFI-2
(Catalog# : 52113, Cas# :
1627676-59-8
)
PFI-2 is a potent, selective, and cell-activelysine methyltransferase SETD7inhibitor
Ponatinib (AP24534)
(Catalog# : 52107, Cas# :
943319-70-8
)
Ponatinib (AP24534) is a novel, potent multi-target inhibitor ofAbl, PDGFR, VEGFR2, F
Palbociclib
(Catalog# : 52001, Cas# :
571190-30-2
)
Palbociclib (PD-0332991) is an orally available pyridopyrimidine-derived cyclin-depen
Palbociclib(PD-0332991)HCl
(Catalog# : 52011, Cas# :
827022-32-2
)
Palbociclib (PD-0332991) HCl is a highly selective inhibitor ofCDK4/6withIC50of 11 nM
Palbociclib (PD0332991) Isethionate
(Catalog# : 52012, Cas# :
827022-33-3
)
Palbociclib (PD0332991) Isethionate is a highly selective inhibitor ofCDK4/6withIC50o
PF-06463922
(Catalog# : 51701, Cas# :
1454846-35-5
)
PF-06463922 is an orally available, ATP-competitive inhibitor of the receptor tyrosin
«
4
5
6
7
8
9
10
»
Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
N-Methylamisulpride ( Synonyms: LB-102 )
(Catalog# : 26A058, Cas# :
2227154-23-4
)
N-Methylamisulpride (Synonyms: LB-102) is a dopamine D2 and D3 receptor antagonist an
Safusidenib Erbumine
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Repinatrabit ( Synonyms: JNT-517 )
(Catalog# : 26A056, Cas# :
2837993-05-0
)
Repinatrabit (JNT-517) is an investigational, selective, small-molecule inhibitor of
Privosegtor ( Synonyms: OCS-05, ACT-01 )
(Catalog# : 26A055, Cas# :
1361200-34-1
)
Privosegtor (OCS-05, ACT-01) is a small molecule peptidomimetic, BDNF/NT-3 growth fac
ART-6043
(Catalog# : 26A054, Cas# :
2923356-52-7
)
ART-6043 is an oral, small-molecule inhibitor of the DNA polymerase theta (POLQ).
Palacaparib ( Synonyms: AZD-9574 )
(Catalog# : 26A053, Cas# :
2756333-39-6
)
Palacaparib (AZD-9574) is an orally available, CNS penetrant, PARP-1 inhibitor.
IPG-7236
(Catalog# : 26A052, Cas# :
2756350-91-9
)
IPG-7236 is a C-C chemokine receptor type 8 (CCR8) antagonist.
Mocaciclib ( Synonyms: Q-901 )
(Catalog# : 26A051, Cas# :
2766124-39-2
)
Mocaciclib (Q-901) is a cyclin-dependent kinase-7 (CDK-7) inhibitor.
Eratrectinib ( Synonyms: VC-004 )
(Catalog# : 26A050, Cas# :
2396516-98-4
)
Eratrectinib (VC-004) is a small molecule inhibitor of the nerve growth factor recept
SCY-770 ( Synonyms: PXL-770 )
(Catalog# : 26A049, Cas# :
1523493-78-8
)
SCY-770 (PXL-770) is a direct adenosine monophosphate-activated protein kinase (AMPK)