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Membrane Transporter/Ion Channel
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Neuronal Signaling
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index P
PF-06873600
(Catalog# : 191145, Cas# :
2185857-97-8
)
PF-06873600 is an orally bioavailable, cyclin-dependent kinase (CDK) inhibitor, with
PF04418948
(Catalog# : 191141, Cas# :
1078166-57-0
)
PF-04418948 is a novel, potent and selective prostaglandin EP2 receptor antagonist.
PF74
(Catalog# : 1812253, Cas# :
1352879-65-2
)
PF-3450074, also known as PF74, is a HIV-1 inhibitor that targets HIV capsid protein.
PT2385
(Catalog# : 1812135, Cas# :
1672665-49-4
)
PT2385 is an orally active, small molecule inhibitor of hypoxia inducible factor (HIF
PF 1022A
(Catalog# : 1811232, Cas# :
133413-70-4
)
PF1022A is a novel anthelmintic that binds to the latrophilin-like transmembrane rece
Pralatrexate
(Catalog# : 1811221, Cas# :
146464-95-1
)
Pralatrexate is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibit
PF-05231023
(Catalog# : 1811162, Cas# :
1037589-69-7
)
PF-05231023 is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and imp
PA-8
(Catalog# : 1810254, Cas# :
878437-15-1
)
A-8 is a small-molecule antagonist of the PAC1 receptor.
Pyronaridine Tetraphosphate
(Catalog# : 1810242, Cas# :
76748-86-2
)
Pyronaridine Tetraphosphate is an antimalarial agent, blocking B-hematin formation, i
PH-002
(Catalog# : 1810234, Cas# :
1311174-68-1
)
PH-002 is a novel inhibitor of apolipoprotein (apo) E4 intramolecular domain interact
Pemigatinib (INCB054828)
(Catalog# : 1810164, Cas# :
1513857-77-6
)
Pemigatinib (INCB054828) is an orally active, selectiveFGFRinhibitor withIC50s of 0.4
Pelitrexol
(Catalog# : 189131, Cas# :
446022-33-9
)
Pelitrexol is a GARFT inhibitor, and is also a water soluble antifolate with anti-pro
PCI-33380
(Catalog# : 18943, Cas# :
1022899-36-0
)
PCI-33380 was designed based on the ibrutinib scaffold and has been used in both cell
Perastine
(Catalog# : 187164, Cas# :
4960-10-5
)
Perastine is a biochemical.
PCO371
(Catalog# : 187125, Cas# :
1613373-33-3
)
PCO371 is a potent and selective PTHR1 agonist for the treatment of hypoparathyroidis
PQR530
(Catalog# : 18756, Cas# :
1927857-61-1
)
PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor.
Pyrotinib
(Catalog# : 18731, Cas# :
1269662-73-8
)
Pyrotinibm, also known as SHR-1258, is an orally bioavailable, dual kinase inhibitor
PX20606 trans-isomer
(Catalog# : 186274, Cas# :
1268244-85-4
)
PX20606, also known as PX-102, is a FXR agonist.
PF-05180999
(Catalog# : 186153, Cas# :
1394033-54-5
)
PF-05180999 is a potent and selective PDE2a inhibitor (PDE2a IC50 = 0.001 μM, 2000-f
Pritelivir mesylate
(Catalog# : 186152, Cas# :
1428333-96-3
)
Pritelivir, also known as AIC-316 and BAY 57-1293, is a potent helicase primase inhib
Pridopidine
(Catalog# : 18673, Cas# :
346688-38-8
)
Pridopidine, also known as ACR16, is a dopamine stabilizer, which improves motor perf
Pamiparib
(Catalog# : 185233, Cas# :
1446261-44-4
)
Pamiparib is an antineoplastic drug candidate.Pamiparib (BGB-290) is an investigation
PAC 14028
(Catalog# : 185223, Cas# :
1005168-10-4
)
PAC 14028, also known as Asivatrep, is a vanilloid VR1 receptor (TRPV1) antagonist po
PE859
(Catalog# : 185157, Cas# :
1402727-29-0
)
PE859 is a potent inhibitor of both tau and Aβ aggregation with IC50 values of 0.66
PD 168 077
(Catalog# : 185156, Cas# :
190383-31-4
)
PD168077 is a dopamine D4 receptor agonist which has a facilitatory effect on memory
PF-06462894
(Catalog# : 185155, Cas# :
1622291-66-0
)
PF-06462894 is a morpholinopyrimidone mGlu5 (mGlu5 Ki = 6 nM).
PF-06291874
(Catalog# : 185154, Cas# :
1393124-08-7
)
PF-06291874 is a glucagon receptor antagonist and potentially usefully for patients w
Poseltinib
(Catalog# : 185153, Cas# :
1353552-97-2
)
Poseltinib, also known HM-71224 and LY3337641, is a tyrosine kinase inhibitor.
Pibrentasvir
(Catalog# : 185148, Cas# :
1353900-92-1
)
Pibrentasvir, also known as ABT-530, is a protease inhibitor potentially for the trea
PP2 Analog
(Catalog# : 185147, Cas# :
309739-67-1
)
PP2 Analog is an analog of PP2 that acts as a protein trafficking modulator.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi