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PF-06424439

Catalog No: 020202
CAS Number: 1469284-78-3
Purity: 98% 

 PF-06424439 is a potent and selective Diacylglycerol Acyltransferase 2 ( DGAT2) inhibitor with DGAT2 IC50 SEM (nM) (human/rat/dog) 14 1/38 4/16 1. 

For research use only. We do not sell to patients.

Chemical Information

NamePF-06424439
Iupac Chemical Name(R)-(1-(2-(1-(4-chloro-1H-pyrazol-1-yl)cyclopropyl)-3H-imidazo[4,5-b]pyridin-5-yl)piperidin-3-yl)(pyrrolidin-1-yl)methanone 
SynonymsPF06424439; PF 06424439 
Molecular FormulaC22H26ClN7O 
Molecular Weight439.94 
SmileO=C([C@H]1CN(C2=CC=C3C(NC(C4(N5N=CC(Cl)=C5)CC4)=N3)=N2)CCC1)N6CCCC6
InChiKeyPZHNKPBYOPQTRG-OAHLLOKOSA-N
InChiInChI=1S/C22H26ClN7O/c23-16-12-24-30(14-16)22(7-8-22)21-25-17-5-6-18(26-19(17)27-21)29-11-3-4-15(13-29)20(31)28-9-1-2-10-28/h5-6,12,14-15H,1-4,7-11,13H2,(H,25,26,27)/t15-/m1/s1
CAS Number1469284-78-3
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

020202 - PF-06424439 | CAS 1469284-78-3

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