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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index P
propan-2-yl (2S)-2-[[(2,3,4,5,6-pentafluorophenoxy)-phenoxyphosphoryl]amino]propanoate
(Catalog# : 102302, Cas# :
1334513-02-8
)
Coming soon!
PF-562271 benzenesulfonate salt
(Catalog# : 101919, Cas# :
939791-38-5
)
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion
2-Pyrimidineacetonitrile (9CI)
(Catalog# : 101903, Cas# :
59566-45-9
)
Coming soon!
PF06447475
(Catalog# : 101601, Cas# :
1527473-33-1
)
PF-06447475 is a highly potent, selective, brain penetrant LRRK2 inhibitor with IC0 o
Pluripotin(SC-1)
(Catalog# : 100502, Cas# :
839707-37-8
)
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small mol
PTP1B-IN-1
(Catalog# : 92302, Cas# :
612530-44-6
)
Coming soon!
Piboserod
(Catalog# : 92301, Cas# :
152811-62-6
)
Piboserod , also known as SB-207266, is a selective 5-HT4 receptor antagonist which w
Pyrrolidin-1-yl-acetic acid hydrochloride
(Catalog# : 92206, Cas# :
6628-74-6
)
Coming soon!
phenyl 2-(benzyloxy)-3-(dibenzylamino)-5-fluoro-6-methylbenzoate
(Catalog# : 91806, Cas# :
1253799-29-9
)
Coming soon!
3-Piperazinobenzisothiazole Hydrochloride
(Catalog# : 91409, Cas# :
144010-02-6
)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
3-(1-Piperazinyl)-1,2-Benzisothiazole
(Catalog# : 91408, Cas# :
87691-87-0
)
The related APILurasidone hydrochlorideThe related intermediates4-(1,2-Benzothiazol-3
3-(4-phenoxyphenyl)propanoic acid
(Catalog# : 90709, Cas# :
20062-91-3
)
Coming soon!
PFI-4
(Catalog# : 82406, Cas# :
900305-37-5
)
PFI-4 is a potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits
Piperazin-2-ylmethanol dihydrochloride
(Catalog# : 81821, Cas# :
122323-87-9
)
Coming soon!
Piperazine-2-Carboxylic Acid Methyl Ester Dihydrochloride
(Catalog# : 81817, Cas# :
122323-88-0
)
Coming soon!
Piperazine-2-carboxylic acid dihydrochloride
(Catalog# : 81814, Cas# :
3022-15-9
)
Coming soon!
Pimecrolimus
(Catalog# : 81302, Cas# :
137071-32-0
)
Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic rec
Pitavastatin Calcium
(Catalog# : 81301, Cas# :
147526-32-7
)
Pitavastatin is a member of the blood cholesterol lowering medication class of statin
PKI-587
(Catalog# : 73109, Cas# :
1197160-78-3
)
PKI-587 is a potent inhibitor to PI3K-, PI3K-, and mTOR (FRAP) with IC50 of 0.4 nM, 5
PFK-015
(Catalog# : 52824, Cas# :
4382-63-2
)
PFK-015 is an effective inhibitor of PFKFB3 with IC50 of 110 nM (recombinant PFKFB3)
Pramiracetam
(Catalog# : 52817, Cas# :
68497-62-1
)
Pramiracetam is a nootropic drug derived from piracetam, and is more potent. Pramirac
PF-573228
(Catalog# : 52816, Cas# :
869288-64-2
)
PF-573228 is a potent and selective FAK inhibitor with IC50 of 4 nM for inhibiton of
Paromomycin Sulfate
(Catalog# : 52815, Cas# :
1263-89-4
)
Paromomycin Sulfate is an aminoglycoside antibiotics inhibiting protein synthesis in
PLX647
(Catalog# : 52756, Cas# :
873786-09-5
)
PLX647 is a highly specific dual FMS/KIT kinase inhibitor with IC50 of 28/16 nM respe
Pexidartinib
(Catalog# : 52753, Cas# :
1029044-16-3
)
pexidartinib is acapsule formulation containing a small-molecule receptor tyrosine ki
PF-543
(Catalog# : 52740, Cas# :
1415562-82-1
)
PF-543 is a novel cell-permeant inhibitor of SphK1 with a Ki of 3.6 nM, PF-543 is sph
PSI-7977
(Catalog# : 52718, Cas# :
1190307-88-0
)
PSI-7977(sofosbuvir) is an investigational nucleotide analog for treatment of chronic
Pirfenidone
(Catalog# : 52701, Cas# :
53179-13-8
)
Pirfenidone(AMR69) is an inhibitor for TGF- production and TGF- stimulated collagen p
Poziotinib
(Catalog# : 52634, Cas# :
1092364-38-9
)
Poziotinib(NOV120101; HM781-36B) is an irreversible Pan-HER inhibitor with IC50s of 3
PF-4708671
(Catalog# : 52631, Cas# :
1255517-76-0
)
PF-4708671 is a novel cell-permeable inhibitor of S6K1 (p70 ribosomal S6 kinase 1), w
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi