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Angiogenesis
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index P
Panobinostat
(Catalog# : 17022809, Cas# :
404950-80-7
)
Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentration
Pelitinib
(Catalog# : 17022702, Cas# :
257933-82-7
)
Pelitinib (EKB-569; WAY-EKB 569) is a potent irreversible EGFR inhibitor with IC50 of
PCI-34051
(Catalog# : 17022402, Cas# :
950762-95-5
)
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor with >200-fol
Psoralen
(Catalog# : 17021307, Cas# :
66-97-7
)
Psoralen is a naturally occurring furocoumarin that intercalates with DNA, inhibiting
P7C3-A20
(Catalog# : 16122838, Cas# :
1235481-90-9
)
P7C3-A20 is an analogue of P7C3, and is a proneurogenic, neuroprotective agent. P7C3-
P7C3
(Catalog# : 16122837, Cas# :
301353-96-8
)
P7C3 is a proneurogenic, neuroprotective agent. P7C3 protects newborn neurons from ap
3PO
(Catalog# : 161227109, Cas# :
13309-08-5
)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
P5091 (P005091)
(Catalog# : 16122795, Cas# :
882257-11-6
)
P5091(P005091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (
PYR-41
(Catalog# : 16122793, Cas# :
418805-02-4
)
PYR-41 is the first cell-permeable inhibitor of ubiquitin-activating enzyme E1, with
PRI-724
(Catalog# : 16122785, Cas# :
847591-62-2
)
PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
PLX7904
(Catalog# : 16122777, Cas# :
1393465-84-3
)
PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor.
Pamapimod (R-1503, Ro4402257)
(Catalog# : 16122774, Cas# :
449811-01-2
)
Pamapimod (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activate
PRIMA-1
(Catalog# : 16122770, Cas# :
5608-24-2
)
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of huma
Picolinamide
(Catalog# : 16122714, Cas# :
1452-77-3
)
Picolinamide is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuc
PD0166285
(Catalog# : 16122710, Cas# :
185039-89-8
)
PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentratio
Peficitinib (ASP015K, JNJ-54781532)
(Catalog# : 16122707, Cas# :
944118-01-8
)
Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
PF-543 Citrate
(Catalog# : 6111525, Cas# :
1415562-83-2
)
PF-543 Citrate is a novel cell-permeant inhibitor of SphK1 with a K(i) of 3.6 nM, PF-
Pasireotide
(Catalog# : 61115, Cas# :
396091-73-9
)
Pasireotide(SOM 230) is a stable cyclohexapeptide somatostatin mimic that exhibits un
PFI-3
(Catalog# : 6111020, Cas# :
1819363-80-8
)
PFI-3
PF-2771
(Catalog# : 611943)
PF-2771 is a potent, selective CENP-E inhibitor, PF-2771 inhibits CENP-E motor activi
PF-04929113 Mesylate
(Catalog# : 611939, Cas# :
1173111-67-5
)
PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median
PI4KIIIbeta-IN-9
(Catalog# : 611908, Cas# :
1429624-84-9
)
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
PI4KIIIbeta-IN-10
(Catalog# : 611907, Cas# :
1881233-39-1
)
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very
PI3Kα inhibitor 1
(Catalog# : 611903, Cas# :
1235449-52-1
)
PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, comp
PF-04979064
(Catalog# : 611902, Cas# :
1220699-06-8
)
PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50)
PQR620
(Catalog# : 611821, Cas# :
1927857-56-4
)
PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects
PP121
(Catalog# : 161009011, Cas# :
1092788-83-4
)
PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyros
PF-4989216
(Catalog# : 161009002, Cas# :
1276553-09-3
)
PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently
PIK-294
(Catalog# : 160926013, Cas# :
900185-02-6
)
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110
PIK-90
(Catalog# : 160926010, Cas# :
677338-12-4
)
PIK-90 is a potent PI3K inhibitor with potential anticancer activity.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran