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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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PROTAC
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index P
Prexasertib free base
(Catalog# : L20345, Cas# :
1234015-52-1
)
Prexasertib, also know LY2606368, is a n inhibitor of checkpoint kinase 1 (chk1) with
Parsaclisib HCl
(Catalog# : L20333, Cas# :
1995889-48-9
)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes w
Parsaclisib free base
(Catalog# : L20332, Cas# :
1426698-88-5
)
Parsaclisib, also known as INCB050465, is a novel PI3Kδ inhibitor which synergizes w
Paltusotine ( CRN-00808 )
(Catalog# : 20294, Cas# :
2172870-89-0
)
Paltusotine is a new class of oral, selective, nonpeptide, somatostatin receptor type
PS210
(Catalog# : 20282, Cas# :
1221962-86-2
)
PS210 is a substrate-selective inhibitor of protein kinase PDK1. It acts by binding t
PD-159206
(Catalog# : 20278, Cas# :
171744-42-6
)
PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HI
3PO
(Catalog# : 21227, Cas# :
18550-98-6
)
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO
PF-06802861 ( ARRY 371797 ; ARRY-797 )
(Catalog# : 2073108, Cas# :
1034189-82-6
)
ARRY 797 (also known as ARRY 371797 or PF 06802861) is an orally active, selective p3
PF-04745637
(Catalog# : 2071623, Cas# :
1917294-46-2
)
PF-04745637 is a TRPV1 antagonist.
Pepstatin
(Catalog# : 2071607, Cas# :
26305-03-3
)
Pepstatin inhibits the aspartic protease endothiapepsin.
PF-477736
(Catalog# : 2071540, Cas# :
952021-60-2
)
PF-477736, also known as PF-00477736, is a potent CHK1 inhibitor with potential chemo
PF-06869206
(Catalog# : 2071506, Cas# :
2227425-05-8
)
PF-06869206 is an Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Co
Pimodivir ( VX-787 )
(Catalog# : 2071401, Cas# :
1629869-44-8
)
Pimodivir, also known as VX-787, JNJ-872, is a novel inhibitor of influenza virus rep
p-Aminophenol sulfate
(Catalog# : 2062201, Cas# :
85278-22-4
)
3-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
(Catalog# : 2062020, Cas# :
26033-20-5
)
Preladenant
(Catalog# : 2061707, Cas# :
377727-87-2
)
Preladenant, also known as SCH 420814, is a potent and selective antagonist at the ad
Paquinimod
(Catalog# : 2061706, Cas# :
248282-01-1
)
Paquinimod, also known as ABR‑215757, is a S100A9 inhibitor preventing S100A9 bindi
PDM-2
(Catalog# : 2061301, Cas# :
688348-25-6
)
PDM-2 is an analog of resveratrol acting as a potent and selective aryl hydrocarbon r
PU-WS13
(Catalog# : 206701, Cas# :
1454619-14-7
)
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-
2,6-Pyridinedicarboxaldehyde
(Catalog# : S-204148, Cas# :
5431-44-7
)
Piperazine, 1-[(1aR,10bS)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-, hydrochloride (1:1), rel-
(Catalog# : S-204141, Cas# :
312905-21-8
)
PZ-2891
(Catalog# : 193282, Cas# :
2170608-82-7
)
PZ-2891 is a potent and selective, orally active Pantothenate kinase (PANK) modulator
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846 is a potent ketohexokinase (KHK) inhibitor.
PTI-428(PTI428)
(Catalog# : 31619, Cas# :
1953130-87-4
)
PTI-428 is a type of CFTR modulator called an amplifier. Amplifiers increase the amou
PF-05085727
(Catalog# : 1932011, Cas# :
1415637-72-7
)
PF-05085727 is a Potent, Selective, and Brain Penetrant Phosphodiesterase 2A Inhibito
Petesicatib
(Catalog# : 193206, Cas# :
1252637-35-6
)
Petesicatib is a cathepsin inhibitor drug candidate.
Pyridone 6
(Catalog# : 193204, Cas# :
457081-03-7
)
Pyridone 6, also known CMP 6 or JAK Inhibitor I, is a pan-Janus-activated kinase inhi
Pretomanid
(Catalog# : 193110, Cas# :
187235-37-6
)
Pretomanid, aslo known as PA-824, a bioreductive drug. PA-824 has potent in vitro act
PF-4136309
(Catalog# : 192282, Cas# :
1341224-83-6
)
PF-4136309, also known as INCB8761, is an orally available human chemokine receptor 2
Palifosfamide
(Catalog# : 192272, Cas# :
31645-39-3
)
Palifosfamide, also known as ZIO201, is a synthetic mustard compound with potential a
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi