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Name Index P

• PFI-3 (Catalog# : 6111020, Cas# : 1819363-80-8)PFI-3
• PF-2771 (Catalog# : 611943)PF-2771 is a potent, selective CENP-E inhibitor, PF-2771 inhibits CENP-E motor activity with an IC50 of 16.1 1.2 nM. PF-2771 is a potent, noncompetitive, selective inhibitor o
• PF-04929113 Mesylate (Catalog# : 611939, Cas# : 1173111-67-5)PF-04929113 Mesylate is a potent and selective Hsp90 inhibitor with an IC50 of median 50 nM. 
• PI4KIIIbeta-IN-9 (Catalog# : 611908, Cas# : 1429624-84-9)PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selective over PI3K and >20-fold selective over PI3K, and shows no inhibition of vps34 at concent
• PI4KIIIbeta-IN-10 (Catalog# : 611907, Cas# : 1881233-39-1)PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very minor off-target inhibition of PI4KIII related lipid kinases (IC50 = 3.6 nM). PI4KII
• PI3Kα inhibitor 1 (Catalog# : 611903, Cas# : 1235449-52-1)PI3Kα inhibitor 1 is a PI3Kα inhibitor extracted from patent US/20120088764A1, compound 243, has an IC50 < 0.1 μM, PI3Kα inhibitor 1 also inhibits HDAC (0.1 μM ≤ IC50 ≤ 1 μM
• PF-04979064 (Catalog# : 611902, Cas# : 1220699-06-8)PF-04979064 is a potent and selective PI3K/mTOR dual kinase inhibitor with an IC(50) of 9.1nM. PF-04979064 exhibited excellent in vitro potency, very good solubility, high LipE
• PQR620 (Catalog# : 611821)PRQ620 is a highly potent and selective mTORC1/2 inhibitor, shows anti-tumor effects in vitro and in vivo. PQR620 demonstrated its potency to prevent cancer cell growth in an N
• PP121 (Catalog# : 161009011, Cas# : 1092788-83-4)PP121 blocks the proliferation of tumor cells by direct inhibition of oncogenic tyrosine kinases and phosphatidylinositol-3-OH kinases.
• PF-4989216 (Catalog# : 161009002, Cas# : 1276553-09-3)PF-4989216 inhibits the phosphorylation of PI3K downstream molecules and subsequently leads to inhibition in cell proliferation and xenograft tumor growth in NSCLCs harboring a P
• PIK-294 (Catalog# : 160926013, Cas# : 900185-02-6)PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110 with an IC50 value of 10 nM compared to IC50 values of 10 M, 490 nM and 160 nM for PI3K//, r
• PIK-90 (Catalog# : 160926010, Cas# : 677338-12-4)PIK-90 is a potent PI3K inhibitor with potential anticancer activity.
• PIK-93 (Catalog# : 160926009, Cas# : 593960-11-3)PIK-93 is a potent PI3K inhibitor. PIK93 selectively inhibits the type III PI 4-kinase beta enzyme, and small interfering RNA-mediated down-regulation of the individual PI 4-kina
• PI-103 (Catalog# : 160926002, Cas# : 371935-74-9)It inhibits ATR and ATM only at much higher concentrations (IC50= 850 and 920 nM, respectively) and exhibits little activity towards a panel of more than 40 other kinases even at
• PNU-159682 (Catalog# : 16071409, Cas# : 202350-68-3)PNU-159682 is a major active metabolite of nemorubicin (MMDX) in human liver microsomes. PNU-159682 showed > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin
• Pevonedistat (Catalog# : 16071408, Cas# : 905579-51-3)Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. NAE inhibitor MLN4924 bin
• PRX-08066 (Catalog# : 16071114, Cas# : 866206-54-4)PRX-08066 is a a novel 5-hydroxytryptamine receptor 2B antagonist, reduces monocrotaline-induced pulmonary arterial hypertension and right ventricular hypertrophy in rats. In the
• PS 48 (Catalog# : 16071111, Cas# : 1180676-32-7)PS 48 has been shown to be a PKB Kinase (phosphoinositide-dependent protein kinase-1, PDK1) activator (Kd= 10.3 M). Studies have indicated that this compound selectively binds to
• Panulisib (Catalog# : 16071030, Cas# : 1356033-60-7)Panulisib, also known as AK151761, is a potent and selective imidazoquinoline based PI3K inhibitor with potential anticancer activity.
• Piclidenoson (Catalog# : 16071028, Cas# : 152918-18-8)Piclidenoson, also known as CF101, is a specific agonist to the A3 adenosine receptor, which inhibits the development of colon carcinoma growth in cell cultures and xenograft mur
• Pirarubicin (Catalog# : 16070806, Cas# : 72496-41-4)Pirarubicin is an anthracycline drug. An analogue of the anthracycline antineoplastic antibiotic doxorubicin. Pirarubicin intercalates into DNA and interacts with topoisomerase I
• PS47 (Catalog# : 16070703, Cas# : 1180676-33-8)PS47
• PIK-293 (Catalog# : 16062804, Cas# : 900185-01-5)PIK-293 is a PI3K inhibitor
• 5-pyridin-4-yl-2,4-dihydro-3H-1,2,4-triazole-3-thione (Catalog# : 16062108, Cas# : 1477-24-3)5-PYRIDIN-4-YL-4H-[1,2,4]TRIAZOLE-3-THIOL
• Paritaprevir (Catalog# : 16060702, Cas# : 1216941-48-8)Paritaprevir, also known as ABT-450, is an acylsulfonamide inhibitor of the NS3-4A serine protease manufactured by Abbott Laboratories that shows promising results as a treatment
• PXD-101 (Catalog# : 16053002, Cas# : 866323-14-0)Belinostat (trade name Beleodaq, previously known as PXD101) is a histone deacetylase inhibitor drug
• PS-1145 (Catalog# : 032501, Cas# : 431898-65-6)Coming soon!
• 2-Pyridinemethanamine, N-[2-(diphenylphosphino)ethyl]- (Catalog# : 032407, Cas# : 1388712-98-8)Coming soon!
• PF-06424439 (Catalog# : 020202, Cas# : 1469284-78-3)PF-06424439 is a potent and selective Diacylglycerol Acyltransferase 2 ( DGAT2) inhibitor with DGAT2 IC50 SEM (nM) (human/rat/dog) 14 1/38 4/16 1.
• PF-06471553 (Catalog# : 020201, Cas# : 1808094-07-6)PF-06471553 is a potent and selective Monoacylglycerol acyltransferase 3 (MGAT3) inhibitor.