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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index P
PF-06650833
(Catalog# : 17988, Cas# :
1817626-54-2
)
PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4). RA
Prexasertib mesylate
(Catalog# : 17986, Cas# :
1234015-55-4
)
Prexasertib, also known as LY2606368, is a potent and selective Chk1/Chk2 inhibitor.
PF-01247324
(Catalog# : 1781102, Cas# :
875051-72-2
)
PF-01247324 is a novel selective and orally bioavailable Nav 1.8 channel blocker, att
PD166866
(Catalog# : 178814, Cas# :
192705-79-6
)
PD166866 has clear antiproliferative effects.
Perindoprilat
(Catalog# : 2017829, Cas# :
95153-31-4
)
Perindoprilat is a potent and long-acting angiotensin converting enzyme inhibitor, ca
PF 04929113
(Catalog# : 2017826, Cas# :
908115-27-5
)
PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-
Palonosetron
(Catalog# : 2017080119, Cas# :
135729-61-2
)
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemothera
Propamocarb hydrochloride
(Catalog# : 2017080115, Cas# :
25606-41-1
)
Propamocarb hydrochloride is an efficient, broad-spectrum, carbamate fungicide safe.
PF-06747775
(Catalog# : 175161, Cas# :
1776112-90-3
)
PF-06747775(PF06747775;CAS 1776112-90-3) is an orally available inhibitor of the epid
PF-04995274
(Catalog# : 17031017, Cas# :
1331782-27-4
)
PF-04995274 is a 5-HT4 receptor partial agonist. It thought to act centrally as a pro
Pilsicainide HCl
(Catalog# : 17031016, Cas# :
88069-49-2
)
Pilsicainide, also known as SUN 1165, is a drug used clinically in Japan to treat car
PNU-74654
(Catalog# : 17031011, Cas# :
113906-27-7
)
PNU-75654 disrupts the Wnt signaling pathway via inhibition of the interaction (KD5
PACAP 1-27
(Catalog# : 17031005, Cas# :
127317-03-7
)
Pituitary adenylate cyclase activating polypeptide (PACAP 1-27) is a potent PACAP re
Ponesimod
(Catalog# : 17030918, Cas# :
854107-55-4
)
Ponesimod, also known as ACT-128800, is a potent, and orally active selective S1P(1)
Pimobendan
(Catalog# : 17030916, Cas# :
74150-27-9
)
Pimobendan is a veterinary medication. Pimobendan is both a calcium sensitizer and a
PFK-158
(Catalog# : 17030915, Cas# :
1462249-75-7
)
PFK-158, also known as ACT-PFK-158, is an inhibitor of 6-phosphofructo-2-kinase/fruct
PH-797804
(Catalog# : 17030914, Cas# :
586379-66-0
)
PH-797804 is a potent and selectiove inhibitor of p38 mitogen-activated protein (MAP)
PIK-75
(Catalog# : 17030913, Cas# :
372196-67-3
)
PIK-75 was developed as part of a PI 3-kinase drug discovery program. PIK75 attenuate
PF-05089771
(Catalog# : 17030912, Cas# :
1235403-62-9
)
PF-05089771 is a Selective Nav1.7 Inhibitor (IC50 = 11 nM) that interacts with the vo
PF-CBP1
(Catalog# : 17030716)
PF-CBP1, also known as PF-06670910, is potent and highly-selective inhibitor of the b
Piperoxan HCl
(Catalog# : 17030708, Cas# :
135-87-5
)
Piperoxan, also known as benodaine, is a drug which was the very first antihistamine
PFI-1
(Catalog# : 17030704, Cas# :
1403764-72-6
)
PFI-1 is a potent and highly selective protein interaction Inhibitor, which targets B
Pirmenol
(Catalog# : 17030702, Cas# :
68252-19-7
)
Pirmenol is an antiarrhythmic agent. Pirmenol inhibits muscarinic acetylcholine recep
Ponatinib HCl
(Catalog# : 17030607, Cas# :
1114544-31-8
)
Ponatinib, also known as AP24534 is an oral drug for the treatment of chronic myeloid
PD-161570
(Catalog# : 17030304, Cas# :
192705-80-9
)
PD-161570 is a selective FGFR inhibitor (IC50 values are 40, 262 and 3700 nM for FGFR
PF-06273340
(Catalog# : 17030201, Cas# :
1402438-74-7
)
PF-06273340 is a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor wit
PF-8380
(Catalog# : 17030115, Cas# :
1144035-53-9
)
PF-8380 is a potent autotaxin inhibitor with an IC(50) of 2.8 nM in isolated enzyme a
Pleconaril
(Catalog# : 17030111, Cas# :
153168-05-9
)
Pleconaril is an antiviral drug potentially for the treatment of enterovirus infectio
Panobinostat
(Catalog# : 17022809, Cas# :
404950-80-7
)
Panobinostat(LBH-589) is a broad-spectrum HDAC inhibitor; low nanomolar concentration
Pelitinib
(Catalog# : 17022702, Cas# :
257933-82-7
)
Pelitinib (EKB-569; WAY-EKB 569) is a potent irreversible EGFR inhibitor with IC50 of
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
EP6
(Catalog# : 25161, Cas# :
1353567-32-4
)
EP6 is a 5-lipoxygenase (5-LO) inhibitor. 5-LO is a crucial enzyme of the arachidonic
Elzovantinib
(Catalog# : 25160, Cas# :
2271119-26-5
)
Elzovantinib, also known as TPX-0022 and CSF1R-IN-2, is an orally bioavailable CSF1R
APS6-45
(Catalog# : 25159, Cas# :
2188236-41-9
)
APS6-45 is a tumor calibrated inhibitor, showing unique polypharmacology. APS6-45 sho
ARN14494
(Catalog# : 25156, Cas# :
1037837-27-6
)
ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key en
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )
(Catalog# : 25152, Cas# :
946128-88-7
)
Avutometinib ( Synonyms: Ro 5126766; CH5126766 )is a potent and selective dual RAF/ME
NST-628
(Catalog# : 24058, Cas# :
3002056-30-3
)
NST-628 is a potent pan-RAF-MEK molecular glue that prevents the phosphorylation and
Nivegacetor ( Synonyms: RG-6289, RO-7269162)
(Catalog# : 25151, Cas# :
2443487-67-8
)
Nivegacetor (RG-6289, RO-7269162) is an oral gamma-secretase modulator.
MAT2A-IN-9 ( GSK4362676 )
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 ( GSK4362676 ), is a 2-oxoquinazoline derivative, is a potent MAT2A (methi