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SCY-770 ( Synonyms: PXL-770 )

Catalog No: 26A049
CAS Number: 1523493-78-8
Purity: ≧98.0%

SCY-770 (PXL-770) is a direct adenosine monophosphate-activated protein kinase (AMPK) activator evaluated in early clinical development for the oral treatment of autosomal dominant polycystic kidney disease (ADPKD). 

For research use only. We do not sell to patients.

Chemical Information

NameSCY-770 ( Synonyms: PXL-770 )
Iupac Chemical NamePotassium 2-chloro-3-(1-hydroxy-5,6,7,8-tetrahydronaphthalen-2-yl)-6-oxo-5-phenyl-6,7-dihydrothieno[2,3-b]pyridin-4-olate
SynonymsSCY-770; SCY770; SCY 770; PXL-770; PXL770; PXL 770
Molecular FormulaC23H17ClKNO3S
Molecular Weight462.0
Smile[O-]C(C(C(C1=CC=C2CCCCC2=C1O)=C(Cl)S3)=C3N4)=C(C5=CC=CC=C5)C4=O.[K+]
InChiKeyLWVVLKOKCHODDJ-UHFFFAOYSA-M
InChiInChI=1S/C23H18ClNO3S.K/c24-21-17(15-11-10-12-6-4-5-9-14(12)19(15)26)18-20(27)16(13-7-2-1-3-8-13)22(28)25-23(18)29-21;/h1-3,7-8,10-11,26H,4-6,9H2,(H2,25,27,28);/q;+1/p-1
CAS Number1523493-78-8
Related CAS1523493-78-8

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
SolubilitySoluble in DMSO (DMSO : ≥ 100 mg/mL)
HandlingRefer to MSDS
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

26A049 - SCY-770 ( Synonyms: PXL-770 ) | CAS 1523493-78-8

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