Palacaparib (AZD-9574) is an orally available, CNS penetrant, PARP-1 inhibitor.
For research use only. We do not sell to patients.
| Name | Palacaparib ( Synonyms: AZD-9574 ) |
|---|---|
| Iupac Chemical Name | 6-Fluoro-5-[4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl]-N-methylpyridine-2-carboxamide |
| Synonyms | Palacaparib; AZD-9574; AZD9574; AZD 9574 |
| Molecular Formula | C21H22F2N6O2 |
| Molecular Weight | 428.4 |
| Smile | O=C(C1=NC(F)=C(N2CCN(CC3=C(F)C4=C(N=C(C)C(N4)=O)C=C3)CC2)C=C1)NC |
| InChiKey | WXRCLFFPZXJCLS-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H22F2N6O2/c1-12-20(30)27-18-14(25-12)4-3-13(17(18)22)11-28-7-9-29(10-8-28)16-6-5-15(21(31)24-2)26-19(16)23/h3-6H,7-11H2,1-2H3,(H,24,31)(H,27,30) |
| CAS Number | 2756333-39-6 |
| Related CAS | 2756333-39-6 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Light yellow solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |