3PO
Catalog No: 161227109
CAS Number: 13309-08-5
Purity: 98%
3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be useful agents in combination with other drugs that inhibit cancer cell proliferation. PFKFB3 inhibitors suppress glucose uptake, which in turn causes an increase in autophagy. The addition of selective inhibitors of autophagy to 3PO and its more potent derivatives may prove useful as rational combinations for the treatment of cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | 3PO |
|---|---|
| Iupac Chemical Name | 3PO |
| Synonyms | N/A |
| Molecular Formula | C13H10N2O |
| Molecular Weight | 210.236 |
| Smile | c1cc(cnc1)/C=C/C(=O)c2ccncc2 |
| InChiKey | UOWGYMNWMDNSTL-ONEGZZNKSA-N |
| InChi | InChI=1S/C13H10N2O/c16-13(12-5-8-14-9-6-12)4-3-11-2-1-7-15-10-11/h1-10H/b4-3+ |
| CAS Number | 13309-08-5 |
| MDL | MFCD00224002 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
