ART-6043 is an oral, small-molecule inhibitor of the DNA polymerase theta (POLQ).
For research use only. We do not sell to patients.
| Name | ART-6043 |
|---|---|
| Iupac Chemical Name | (3aR,11aS)-6,10-Dimethyl-5-[2-(4-methylpiperazin-1-yl)ethyl]-1-[6-methyl-4-(trifluoromethyl)pyridin-2-yl]-3a,5,10,11a-tetrahydro-1H-pyrrolo[2,3-c][1,6]benzodiazocine-2,11(3H,4H)-dione |
| Synonyms | ART-6043; ART6043; ART 6043 |
| Molecular Formula | C28H35F3N6O2 |
| Molecular Weight | 544.6 |
| Smile | O=C(N1C2=NC(C)=CC(C(F)(F)F)=C2)C[C@@]3([H])[C@@]1([H])C(N(C)C4=CC=CC(C)=C4N(CCN5CCN(C)CC5)C3)=O |
| InChiKey | JCATVBJYPBKEFM-IBVKSMDESA-N |
| InChi | InChI=1S/C28H35F3N6O2/c1-18-6-5-7-22-25(18)36(13-12-35-10-8-33(3)9-11-35)17-20-15-24(38)37(26(20)27(39)34(22)4)23-16-21(28(29,30)31)14-19(2)32-23/h5-7,14,16,20,26H,8-13,15,17H2,1-4H3/t20-,26+/m1/s1 |
| CAS Number | 2923356-52-7 |
| Related CAS | 2923356-52-7 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |