PI4KIIIbeta-IN-10
Catalog No: 611907
CAS Number: 1881233-39-1
Purity: 98%
PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very minor off-target inhibition of PI4KIII related lipid kinases (IC50 = 3.6 nM).
PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2 (IC50 1 M), PI3K (10 M), and PI4KIII (3 M), and <20% inhibition at concentrations up to 20 M for PI4K2, PI4K2, and PI3K. PI4KIIIbeta-IN-10 is also the most effective antiviral compound in a cellular model of hepatitis C virus replication, with the best balance of antiviral potency and low cellular toxicity.
For research use only. We do not sell to patients.
Chemical Information
| Name | PI4KIIIbeta-IN-10 |
|---|---|
| Iupac Chemical Name | PI4KIIIbeta-IN-10 |
| Synonyms | N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide |
| Molecular Formula | C22H25N3O5S2 |
| Molecular Weight | 475.58 |
| InChiKey | |
| InChi | |
| CAS Number | 1881233-39-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
