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Psoralen

Catalog No.: 17021307
Cas No.: 66-97-7
Purity : 98% 
17021307 - Psoralen | CAS 66-97-7

Catalog number : 17021307

CAS number : 66-97-7

Molecular Formula : C11H6O3 

Molecular Weight : 186.16 

Iupac Chemical Name : Psoralen 

Smile : c1cc(=O)oc2c1cc3ccoc3c2

InChiKey : ZCCUUQDIBDJBTK-UHFFFAOYSA-N

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Synonymspsoralene, Ficusin, Furocoumarin 
Molecular FormulaC11H6O3 
Molecular Weight186.16 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
Smilec1cc(=O)oc2c1cc3ccoc3c2
InChiKeyZCCUUQDIBDJBTK-UHFFFAOYSA-N
InChiInChI=1S/C11H6O3/c12-11-2-1-7-5-8-3-4-13-9(8)6-10(7)14-11/h1-6H
MDLMFCD00010520
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Psoralen is a naturally occurring furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.

Psoralen inhibits the proliferation of MCF-7/ADR cells as shown by G0/G1 phase arrest rather than encouraging apoptosis. Psoralen reverses MDR(multidrug resistance) through inhibiting ATPase activity rather than reducing P-gp expression. Psoralen inhibits the migration abilities of MCF-7/ADR cells by repressing EMT possibly through inhibiting the activation of NF-B. Psoralens are photoactive compounds that readily alkylate DNA when activated by longwave ultraviolet light. Proliferation has been significantly promoted in MCF-7/ADR cells treated with low concentration of psoralen (<10.75 M) and inhibited with high concentration(>21.5 M). Psoralen can inhibit metastasis of breast cancer. Psoralen mediates a variety of cell processes including cell death, proliferation, inflammation and migration.

 

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