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PLX7904

Catalog No.: 16122777
Cas No.: 1393465-84-3
Purity : 98% 
16122777 - PLX7904 | CAS 1393465-84-3

Catalog number : 16122777

CAS number : 1393465-84-3

Molecular Formula : C24H22F2N6O3S 

Molecular Weight : 512.53 

Iupac Chemical Name : PLX7904 

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SynonymsPB04 
Molecular FormulaC24H22F2N6O3S 
Molecular Weight512.53 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. 

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