PF-06281355
Catalog No: 1791312
CAS Number: 1435467-38-1
Purity: 98.0%
PF-06281355, also known as PF-1355, is an orally available, selective and potent mechanism based inhibitor of the myeloperoxidase (MPO) that reduces plasma MPO activity, vascular edema, neutrophil recruitment, and elevated circulating cytokines.
For research use only. We do not sell to patients.
Chemical Information
| Name | PF-06281355 |
|---|---|
| Iupac Chemical Name | 2-(6-(2,5-Dimethoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide |
| Synonyms | PF-06281355; PF 06281355; PF06281355; PF-1355; PF 1355; PF1355. |
| Molecular Formula | C14H15N3O4S |
| Molecular Weight | 321.351 |
| Smile | COC1=C(C=C(C=C1)OC)C1=CC(NC(N1CC(=O)N)=S)=O |
| InChiKey | LJBUZOGABRDGBR-UHFFFAOYSA-N |
| InChi | InChI=1S/C14H15N3O4S/c1-20-8-3-4-11(21-2)9(5-8)10-6-13(19)16-14(22)17(10)7-12(15)18/h3-6H,7H2,1-2H3,(H2,15,18)(H,16,19,22) |
| CAS Number | 1435467-38-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ℃ for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
