PF-06747775
Catalog No: 175161
CAS Number: 1776112-90-3
Purity: 98% by HNMR/HPLC
PF-06747775(PF06747775;CAS 1776112-90-3) is an orally available inhibitor of the epidermal growth factor receptor (EGFR) mutant form T790M, with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | PF-06747775 |
|---|---|
| Iupac Chemical Name | N-((3R,4R)-4-fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide |
| Synonyms | PF-06747775;PF06747775;PF 06747775 |
| Molecular Formula | C18H22FN9O2 |
| Molecular Weight | 415.4 |
| Smile | C=CC(N[C@@H]1CN(C2=NC(NC3=CN(C)N=C3OC)=C4N=CN(C)C4=N2)C[C@H]1F)=O |
| InChiKey | JYIUNVOCEFIUIU-GHMZBOCLSA-N |
| InChi | InChI=1S/C18H22FN9O2/c1-5-13(29)21-11-8-28(6-10(11)19)18-23-15(14-16(24-18)26(2)9-20-14)22-12-7-27(3)25-17(12)30-4/h5,7,9-11H,1,6,8H2,2-4H3,(H,21,29)(H,22,23,24)/t10-,11-/m1/s1 |
| CAS Number | 1776112-90-3 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% by HNMR/HPLC |
| Storage | 3 years -20ºCpowder;6 months-80ºCin solvent |
| Solubility | Soluble in DMSO, not in water |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
