PF-05089771
Catalog No: 17030912
CAS Number: 1235403-62-9
Purity: 98%
PF-05089771 is a Selective Nav1.7 Inhibitor (IC50 = 11 nM) that interacts with the voltage-sensor domain (VSD) of domain IV. PF-05089771 exhibits a slow onset of block that is depolarization and concentration dependent, with a similarly slow recovery from block.
For research use only. We do not sell to patients.
Chemical Information
| Name | PF-05089771 |
|---|---|
| Iupac Chemical Name | 4-(2-(5-amino-1H-pyrazol-4-yl)-4-chlorophenoxy)-5-chloro-2-fluoro-N-(thiazol-4-yl)benzenesulfonamide |
| Synonyms | PF-05089771; PF 05089771; PF05089771; PF-05089771; PF05089771; PF 05089771 |
| Molecular Formula | C18H12Cl2FN5O3S2 |
| Molecular Weight | 500.3444 |
| Smile | NC1=C(C=NN1)C1=C(OC2=CC(=C(C=C2Cl)S(=O)(=O)NC=2N=CSC2)F)C=CC(=C1)Cl |
| InChiKey | ZYSCOUXLBXGGIM-UHFFFAOYSA-N |
| InChi | InChI=1S/C18H12Cl2FN5O3S2/c19-9-1-2-14(10(3-9)11-6-24-25-18(11)22)29-15-5-13(21)16(4-12(15)20)31(27,28)26-17-7-30-8-23-17/h1-8,26H,(H3,22,24,25) |
| CAS Number | 1235403-62-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
